脑周围非动脉瘤性蛛网膜下腔出血:是否需要重复数字减影血管造影?

IF 2.6 3区 医学 Q2 CLINICAL NEUROLOGY
Rosa Schubert, Maharani Budi Santoso, Yan Li, Cornelius Deuschl, Ramazan Jabbarli, Ulrich Sure, Michael Forsting, Hanna Styczen
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引用次数: 0

摘要

目的:评价反复数字减影血管造影(DSA)对自发性脑实质周围非动脉瘤性蛛网膜下腔出血(PMSAH)的诊断率和临床意义,并评价DSA相关并发症的发生率。方法:回顾性分析2002年3月至2025年2月82例经非对比CT确诊的PMSAH患者。所有患者平均在24小时内进行首次计算机断层血管造影(CTA)和第一次DSA检查。如果未发现出血源,则在10-14天后进行第二次DSA检查。评估临床资料、影像学表现和并发症。结果:82例患者中76例(92.7%)初始DSA未见血管异常。60/76例(78.9%)患者进行了第二次DSA检查,发现了两个小的基底动脉动脉瘤(3.3%),这些动脉瘤在最初的CTA或DSA上不可见,但在重复3D旋转血管造影(3DRA)上可检测到。3例dsa(2%)出现手术相关并发症,包括小脑梗死、幕上栓塞和局部穿刺部位并发症。大多数患者的临床病程为良性,仅有一例住院死亡。结论:重复DSA对典型PMSAH的诊断价值较低,无明显的治疗效果,且存在并发症的相关风险。考虑到PMSAH的良性进程和高分辨率无创成像的可用性,如双源、光子计数CTA或血管壁MRI,对于有非典型特征或临床恶化的病例,应保留重复DSA。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Perimesencephalic non-aneurysmal subarachnoid hemorrhage: is there a need for repeat digital subtraction angiography?

Purpose: To assess the diagnostic yield and clinical relevance of repeated digital subtraction angiography (DSA) in patients with spontaneous perimesencephalic non-aneurysmal subarachnoid hemorrhage (PMSAH) and to evaluate DSA-related complication rates.

Methods: Retrospective analysis of 82 patients with PMSAH confirmed by non-contrast CT between March 2002 and February 2025. All patients underwent initial computed tomography angiography (CTA) and first DSA on average within 24 h. If no bleeding source was identified, a second DSA was performed after 10-14 days. Clinical data, radiological findings, and complications were evaluated.

Results: The initial DSA showed no vascular abnormality in 76/82 patients (92.7%). A second DSA was performed in 60/76 cases (78.9%) and identified two small basilar artery aneurysms (3.3%) that were not visible on the initial CTA or DSA but were detectable on repeat 3D rotational angiography (3DRA). Procedure-related complications occurred in three DSAs (2%), including a cerebellar infarct, supratentorial embolism, and local puncture site complication. Most patients had a benign clinical course, and only one in-hospital death was documented.

Conclusion: The diagnostic benefit of repeat DSA in typical PMSAH is low, with no clear therapeutic impact and a relevant risk of complications. Given the benign course of PMSAH and the availability of high-resolution non-invasive imaging such as dual-source, photon-counting CTA, or vessel wall MRI, repeat DSA should be reserved for selected cases with atypical features or clinical deterioration.

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来源期刊
Neuroradiology
Neuroradiology 医学-核医学
CiteScore
5.30
自引率
3.60%
发文量
214
审稿时长
4-8 weeks
期刊介绍: Neuroradiology aims to provide state-of-the-art medical and scientific information in the fields of Neuroradiology, Neurosciences, Neurology, Psychiatry, Neurosurgery, and related medical specialities. Neuroradiology as the official Journal of the European Society of Neuroradiology receives submissions from all parts of the world and publishes peer-reviewed original research, comprehensive reviews, educational papers, opinion papers, and short reports on exceptional clinical observations and new technical developments in the field of Neuroimaging and Neurointervention. The journal has subsections for Diagnostic and Interventional Neuroradiology, Advanced Neuroimaging, Paediatric Neuroradiology, Head-Neck-ENT Radiology, Spine Neuroradiology, and for submissions from Japan. Neuroradiology aims to provide new knowledge about and insights into the function and pathology of the human nervous system that may help to better diagnose and treat nervous system diseases. Neuroradiology is a member of the Committee on Publication Ethics (COPE) and follows the COPE core practices. Neuroradiology prefers articles that are free of bias, self-critical regarding limitations, transparent and clear in describing study participants, methods, and statistics, and short in presenting results. Before peer-review all submissions are automatically checked by iThenticate to assess for potential overlap in prior publication.
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