在MUHC治疗的首次缺血性卒中患者中未确诊危险因素的患病率:回顾性分析。

IF 3 3区 医学 Q2 HEALTH CARE SCIENCES & SERVICES
Shorog Althubait, Heather Perkins, Robert Cote, Theodore Wein, Jeffrey Minuk, Eric Erhensperger, Liam Durcan, Aimen Moussaddy, Lucy Vieira
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引用次数: 0

摘要

背景:缺血性脑卒中是世界范围内发病率和死亡率的主要原因。尽管建立了预防策略,但许多患者在首次缺血性卒中时存在先前未诊断的血管危险因素(urf),这表明错过了早期发现的机会。在加拿大,特别是在魁北克省,获得初级保健的机会不一致,很大一部分人口缺乏对家庭医生(FD)的依赖。目的:本研究旨在确定首次缺血性卒中患者urf的患病率,并评估urf、地理区域和加拿大魁北克省初级保健可及性之间的关系。我们假设没有FD的患者会有更高的urf患病率。方法:我们对2014年至2017年在麦吉尔大学健康中心(MUHC)收治的610例首次缺血性卒中患者进行了回顾性图表回顾。收集的数据包括人口统计数据;已知和未确诊的卒中危险因素,如高血压(HTN)、糖尿病(DM)、高脂血症(HLD)和心房颤动(AF);FD状态;以及基于邮政编码的地理位置。结果:在610例患者中,136例(22.3%)至少有一次URF。最常见的URF是HLD(14.3%),其次是HTN(6.2%)、AF(1.6%)和DM(0.1%)。在609例可获得数据的患者中,146例(23.97%)缺乏FD。没有FD的患者更容易出现未确诊的HTN (7.6% vs. 2.1%, p = 0.008)。其他urf没有观察到显著差异。URF患病率和FD获取均存在地理差异,但区域差异无统计学意义。结论:我们的研究结果支持这样的假设,即缺乏FD与缺血性卒中患者中未确诊的HTN患病率较高有关。有针对性的筛查和改善获得初级保健的机会,特别是在服务不足的地区,可能有助于通过促进早期识别和管理可改变的风险因素来减轻可预防中风的负担。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

Prevalence of Undiagnosed Risk Factors in Patients with First-Ever Ischemic Stroke Treated at MUHC: A Retrospective Analysis.

Prevalence of Undiagnosed Risk Factors in Patients with First-Ever Ischemic Stroke Treated at MUHC: A Retrospective Analysis.

Background: Ischemic stroke is a leading cause of morbidity and mortality worldwide. Despite established prevention strategies, many patients present with previously undiagnosed vascular risk factors (URFs) at the time of their first-ever ischemic stroke, suggesting missed opportunities for early detection. In Canada, particularly in Quebec, access to primary care is inconsistent, and a substantial proportion of the population lacks attachment to a family doctor (FD). Objective: This study aimed to determine the prevalence of URFs among patients with first-ever ischemic stroke and to evaluate the relationship between URFs, geographic region, and access to primary care in Quebec, Canada. We hypothesized that patients without an FD would have a higher prevalence of URFs. Methods: We conducted a retrospective chart review of 610 patients admitted with first-ever ischemic stroke to the McGill University Health Center (MUHC) between 2014 and 2017. Data collected included demographics; known and undiagnosed stroke risk factors such as hypertension (HTN), diabetes mellitus (DM), hyperlipidemia (HLD), and atrial fibrillation (AF); FD status; and geographic location based on postal code. Results: Among the 610 patients, 136 (22.3%) had at least one URF. The most common URF was HLD (14.3%), followed by HTN (6.2%), AF (1.6%), and DM (0.1%). Of 609 patients with available data, 146 (23.97%) lacked an FD. Patients without an FD were significantly more likely to have undiagnosed HTN (7.6% vs. 2.1%, p = 0.008). No significant differences were observed for the other URFs. Geographic variation was noted in both URF prevalence and FD access, but regional differences were not statistically significant. Conclusions: Our findings support the hypothesis that a lack of an FD is associated with a higher prevalence of undiagnosed HTN in ischemic stroke patients. Targeted screening and improved access to primary care, particularly in underserved regions, may help to reduce the burden of preventable stroke by facilitating the earlier identification and management of modifiable risk factors.

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来源期刊
Journal of Personalized Medicine
Journal of Personalized Medicine Medicine-Medicine (miscellaneous)
CiteScore
4.10
自引率
0.00%
发文量
1878
审稿时长
11 weeks
期刊介绍: Journal of Personalized Medicine (JPM; ISSN 2075-4426) is an international, open access journal aimed at bringing all aspects of personalized medicine to one platform. JPM publishes cutting edge, innovative preclinical and translational scientific research and technologies related to personalized medicine (e.g., pharmacogenomics/proteomics, systems biology). JPM recognizes that personalized medicine—the assessment of genetic, environmental and host factors that cause variability of individuals—is a challenging, transdisciplinary topic that requires discussions from a range of experts. For a comprehensive perspective of personalized medicine, JPM aims to integrate expertise from the molecular and translational sciences, therapeutics and diagnostics, as well as discussions of regulatory, social, ethical and policy aspects. We provide a forum to bring together academic and clinical researchers, biotechnology, diagnostic and pharmaceutical companies, health professionals, regulatory and ethical experts, and government and regulatory authorities.
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