Stefan Rues, Jannis Crocoll, Sebastian Hetzler, Johannes Rossipal, Peter Rammelsberg, Andreas Zenthöfer
{"title":"用3d打印或铣削制造不同壁厚的3单元氧化锆固定牙体的抗断裂性。","authors":"Stefan Rues, Jannis Crocoll, Sebastian Hetzler, Johannes Rossipal, Peter Rammelsberg, Andreas Zenthöfer","doi":"10.3390/jfb16090330","DOIUrl":null,"url":null,"abstract":"<p><strong>Background: </strong>To evaluate the fracture resistance of 3D-printed 3-unit fixed dental prostheses (FDPs) made from tetragonal zirconia polycrystal (3Y-TZP).</p><p><strong>Methods: </strong>Based on a maxillary typodont model with a missing first molar and neighboring teeth with full crown preparations, FDPs differing in wall thickness (d = 0.6 mm / d = 0.8 mm / d = 1.0 mm) were designed. For all test groups, 12 samples were fabricated from 3Y-TZP by either 3D-printing or milling. For 3D-printing, pontic designs were modified by basal slots to enable regular firing times. After luting on CoCr dies, samples underwent artificial aging. Loads tilted by 30° were applied on the mesio-buccal cusp of the pontic, and fracture resistance F<sub>u</sub> was assessed. Welch ANOVA and Dunnett-T3 tests were used for statistical evaluation.</p><p><strong>Results: </strong>Significant differences in F<sub>u</sub> were identified (Welch ANOVA, <i>p</i> < 0.001). For milled FDPs, fracture originated from connector areas, and F<sub>u</sub> increased with increasing wall thickness (d = 0.6 mm: 1536 ± 131 N, d = 0.8 mm: 2226 ± 145 N, d = 1.0 mm: 2686 ± 127 N, significant differences but for the comparison d = 0.8 mm vs. d = 1.0 mm). For 3D-printed FDPs, the loaded cusp fractured, and F<sub>u</sub> did not change with FDP wall thicknesses (<i>p</i> > 0.779, F<sub>u</sub> = 1110 ± 26 N for all PZ FDPs). Milled FDPs showed significantly higher F<sub>u</sub> when compared to 3D-printed FDPs with identical wall thickness.</p><p><strong>Conclusions: </strong>Although 3D-printed zirconia FDPs still show lower fracture resistance values than their milled counterparts, all tested FDP configurations clearly exceed the clinical reference thresholds and can therefore be recommended for clinical use.</p>","PeriodicalId":15767,"journal":{"name":"Journal of Functional Biomaterials","volume":"16 9","pages":""},"PeriodicalIF":5.2000,"publicationDate":"2025-09-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12470422/pdf/","citationCount":"0","resultStr":"{\"title\":\"Fracture Resistance of 3-Unit Zirconia Fixed Dental Prostheses Differing in Wall Thickness Fabricated by Either 3D-Printing or Milling.\",\"authors\":\"Stefan Rues, Jannis Crocoll, Sebastian Hetzler, Johannes Rossipal, Peter Rammelsberg, Andreas Zenthöfer\",\"doi\":\"10.3390/jfb16090330\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Background: </strong>To evaluate the fracture resistance of 3D-printed 3-unit fixed dental prostheses (FDPs) made from tetragonal zirconia polycrystal (3Y-TZP).</p><p><strong>Methods: </strong>Based on a maxillary typodont model with a missing first molar and neighboring teeth with full crown preparations, FDPs differing in wall thickness (d = 0.6 mm / d = 0.8 mm / d = 1.0 mm) were designed. For all test groups, 12 samples were fabricated from 3Y-TZP by either 3D-printing or milling. For 3D-printing, pontic designs were modified by basal slots to enable regular firing times. After luting on CoCr dies, samples underwent artificial aging. Loads tilted by 30° were applied on the mesio-buccal cusp of the pontic, and fracture resistance F<sub>u</sub> was assessed. Welch ANOVA and Dunnett-T3 tests were used for statistical evaluation.</p><p><strong>Results: </strong>Significant differences in F<sub>u</sub> were identified (Welch ANOVA, <i>p</i> < 0.001). For milled FDPs, fracture originated from connector areas, and F<sub>u</sub> increased with increasing wall thickness (d = 0.6 mm: 1536 ± 131 N, d = 0.8 mm: 2226 ± 145 N, d = 1.0 mm: 2686 ± 127 N, significant differences but for the comparison d = 0.8 mm vs. d = 1.0 mm). For 3D-printed FDPs, the loaded cusp fractured, and F<sub>u</sub> did not change with FDP wall thicknesses (<i>p</i> > 0.779, F<sub>u</sub> = 1110 ± 26 N for all PZ FDPs). Milled FDPs showed significantly higher F<sub>u</sub> when compared to 3D-printed FDPs with identical wall thickness.</p><p><strong>Conclusions: </strong>Although 3D-printed zirconia FDPs still show lower fracture resistance values than their milled counterparts, all tested FDP configurations clearly exceed the clinical reference thresholds and can therefore be recommended for clinical use.</p>\",\"PeriodicalId\":15767,\"journal\":{\"name\":\"Journal of Functional Biomaterials\",\"volume\":\"16 9\",\"pages\":\"\"},\"PeriodicalIF\":5.2000,\"publicationDate\":\"2025-09-05\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12470422/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of Functional Biomaterials\",\"FirstCategoryId\":\"5\",\"ListUrlMain\":\"https://doi.org/10.3390/jfb16090330\",\"RegionNum\":3,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"ENGINEERING, BIOMEDICAL\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Functional Biomaterials","FirstCategoryId":"5","ListUrlMain":"https://doi.org/10.3390/jfb16090330","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"ENGINEERING, BIOMEDICAL","Score":null,"Total":0}
引用次数: 0
摘要
背景：研究四方氧化锆多晶（3Y-TZP）三维打印3单元固定义齿（fdp）的抗断裂性能。方法：基于缺失第一磨牙和邻牙全冠预备的上颌型牙模型，设计不同壁厚（d = 0.6 mm / d = 0.8 mm / d = 1.0 mm）的fdp。对于所有测试组，通过3d打印或铣削，用3Y-TZP制作了12个样品。对于3d打印，桥桥设计通过基础槽进行修改，以实现正常的发射时间。样品放置在CoCr模具上后，进行人工老化。将倾斜30°的载荷施加于桥侧中颊尖，并评估抗骨折Fu。采用Welch方差分析和Dunnett-T3检验进行统计评价。结果：Fu有显著差异（Welch方差分析，p < 0.001）。对于铣削后的fdp，裂缝起源于连接器区域，Fu随着壁厚的增加而增加（d = 0.6 mm: 1536±131 N, d = 0.8 mm: 2226±145 N, d = 1.0 mm: 2686±127 N，除了比较d = 0.8 mm和d = 1.0 mm外，差异显著）。对于3d打印的FDP，加载尖端断裂，Fu不随FDP壁厚变化（p > 0.779，所有PZ FDP的Fu = 1110±26 N）。与相同壁厚的3d打印fdp相比，铣削fdp显示出明显更高的Fu。结论：虽然3d打印的氧化锆FDP的抗骨折性值仍然低于研磨的FDP，但所有测试的FDP配置都明显超过了临床参考阈值，因此可以推荐临床使用。
Fracture Resistance of 3-Unit Zirconia Fixed Dental Prostheses Differing in Wall Thickness Fabricated by Either 3D-Printing or Milling.
Background: To evaluate the fracture resistance of 3D-printed 3-unit fixed dental prostheses (FDPs) made from tetragonal zirconia polycrystal (3Y-TZP).
Methods: Based on a maxillary typodont model with a missing first molar and neighboring teeth with full crown preparations, FDPs differing in wall thickness (d = 0.6 mm / d = 0.8 mm / d = 1.0 mm) were designed. For all test groups, 12 samples were fabricated from 3Y-TZP by either 3D-printing or milling. For 3D-printing, pontic designs were modified by basal slots to enable regular firing times. After luting on CoCr dies, samples underwent artificial aging. Loads tilted by 30° were applied on the mesio-buccal cusp of the pontic, and fracture resistance Fu was assessed. Welch ANOVA and Dunnett-T3 tests were used for statistical evaluation.
Results: Significant differences in Fu were identified (Welch ANOVA, p < 0.001). For milled FDPs, fracture originated from connector areas, and Fu increased with increasing wall thickness (d = 0.6 mm: 1536 ± 131 N, d = 0.8 mm: 2226 ± 145 N, d = 1.0 mm: 2686 ± 127 N, significant differences but for the comparison d = 0.8 mm vs. d = 1.0 mm). For 3D-printed FDPs, the loaded cusp fractured, and Fu did not change with FDP wall thicknesses (p > 0.779, Fu = 1110 ± 26 N for all PZ FDPs). Milled FDPs showed significantly higher Fu when compared to 3D-printed FDPs with identical wall thickness.
Conclusions: Although 3D-printed zirconia FDPs still show lower fracture resistance values than their milled counterparts, all tested FDP configurations clearly exceed the clinical reference thresholds and can therefore be recommended for clinical use.
期刊介绍：
Journal of Functional Biomaterials (JFB, ISSN 2079-4983) is an international and interdisciplinary scientific journal that publishes regular research papers (articles), reviews and short communications about applications of materials for biomedical use. JFB covers subjects from chemistry, pharmacy, biology, physics over to engineering. The journal focuses on the preparation, performance and use of functional biomaterials in biomedical devices and their behaviour in physiological environments. Our aim is to encourage scientists to publish their results in as much detail as possible. Therefore, there is no restriction on the length of the papers. The full experimental details must be provided so that the results can be reproduced. Several topical special issues will be published. Scope: adhesion, adsorption, biocompatibility, biohybrid materials, bio-inert materials, biomaterials, biomedical devices, biomimetic materials, bone repair, cardiovascular devices, ceramics, composite materials, dental implants, dental materials, drug delivery systems, functional biopolymers, glasses, hyper branched polymers, molecularly imprinted polymers (MIPs), nanomedicine, nanoparticles, nanotechnology, natural materials, self-assembly smart materials, stimuli responsive materials, surface modification, tissue devices, tissue engineering, tissue-derived materials, urological devices.
求助内容：
应助结果提醒方式：
京公网安备 11010802042870号
