急性A型主动脉夹层需要冠状动脉搭桥术:临床观察、诊断差距和手术结果。

IF 2.3 4区 医学 Q2 CARDIAC & CARDIOVASCULAR SYSTEMS
Mohammed Morjan, Charlotte Philippa Jürgens, Tong Li, Luis Jaime Vallejo Castano, Freya Jenkins, Amin Thwairan, Vivien Weyers, Hannan Dalyanoglu, Sebastian Daniel Reinartz, Artur Lichtenberg
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引用次数: 0

摘要

目的:急性A型主动脉夹层修复术中合并冠状动脉旁路移植术是常见的,且死亡率高。本研究旨在描述患者队列,评估结果,并评估术前诊断在这些高危患者中的作用。方法:纳入2007年3月至2023年6月期间行冠状动脉搭桥术和急性A型主动脉夹层修复术的患者。将住院幸存者和非幸存者进行比较。进行逻辑回归分析以确定住院死亡率的预测因素。术前计算机断层扫描由心血管放射科医生独立审查,以评估潜在的冠状动脉受累。采用Cohen κappa试验评估计算机断层扫描与术中冠状动脉夹层报告的一致性。结果:该队列包括98例患者。住院死亡率为26.5% (n = 26)。右冠状动脉移植最多(57%,n = 56)。术前肌酸激酶升高是院内死亡率的唯一预测因子(p = 0.044)。在72例可用的术前CT扫描中,76% (n = 55)显示冠脉受累,而术中冠脉剥离需要搭桥手术的记录仅为42% (n = 30)。计算机断层扫描与术中解剖报告的一致性较差(κappa 0.043 (95% CI, -0.155 ~ 0.241), p = 0.66)。结论:急性A型主动脉夹层修复术中冠状动脉搭桥术死亡率和发病率较高。右冠状动脉最常受影响。冠状动脉旁路并不总是与冠状动脉夹层相关,这使得术中检测具有挑战性。这强调了术前诊断的重要性,尤其是计算机断层扫描。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Need for Coronary Artery Bypass Grafting in Acute Type A Aortic Dissection: Clinical Insights, Diagnostic Gaps, and Surgical Outcomes.

Objectives: The need for concomitant coronary artery bypass grafting during acute type A aortic dissection repair is common and associated with high mortality. This study aims to characterize the patient cohort, assess outcomes, and evaluate the role of preoperative diagnostics in these high-risk patients. Methods: Patients who underwent concomitant coronary artery bypass and acute type A aortic dissection repair between March 2007 and June 2023 were included. In-hospital survivors and non-survivors were compared. Logistic regression analyses were performed to identify predictors of in-hospital mortality. Preoperative computed tomography scans were independently reviewed by a cardiovascular radiologist to assess potential coronary involvement. The agreement between computed tomography and intraoperative reports of coronary dissection was evaluated using Cohen's κappa test. Results: The cohort consisted of ninety-eight patients. In-hospital mortality was 26.5% (n = 26). The right coronary artery was the most frequently grafted (57%, n = 56). Elevated preoperative creatine kinase was the only predictor of in-hospital mortality (p = 0.044). Of the 72 available preoperative CT scans, 76% (n = 55) indicated coronary involvement, whereas intraoperative coronary dissection requiring bypass grafting was documented in only 42% (n = 30)). The agreement between computer tomography and intraoperative dissection reports was poor (κappa 0.043 (95% CI, -0.155 to 0.241), p = 0.66). Conclusion: Simultaneous coronary artery bypass during acute type A aortic dissection repair remains associated with high mortality and morbidity. The right coronary artery is most often affected. Coronary bypass is not always linked to coronary dissection, making intraoperative detection challenging. This underscores the importance of preoperative diagnostics, especially computer tomography.

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来源期刊
Journal of Cardiovascular Development and Disease
Journal of Cardiovascular Development and Disease CARDIAC & CARDIOVASCULAR SYSTEMS-
CiteScore
2.60
自引率
12.50%
发文量
381
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