麻疹暴发和对加拿大接受干细胞或细胞治疗的患者的影响:加拿大细胞治疗移植(CTTC)传染病工作委员会。

IF 3.4 4区 医学 Q2 ONCOLOGY
Simon F Dufresne, Mohammadreza R Shahmirzadi, Uday Deotare, Dima Kabbani, Shahid Husain, Coleman Rotstein, Seyed M Hosseini-Moghaddam
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引用次数: 0

摘要

自引入常规疫苗接种计划以来,麻疹暴露在历史上很少,导致癌症患者,造血干细胞移植(HCT)接受者,接受细胞治疗(CT)的患者及其医疗保健提供者缺乏关注。必须承认在这些情况下保持警惕的重要性。在北美,麻疹群体免疫力大幅下降,原因是对疫苗的犹豫情绪上升,导致疫情爆发。麻疹可导致严重后果,其再次出现已引起患者和照料HCT/CT接受者的卫生保健专业人员的警惕。患有严重免疫损害的患者不能接种减毒活疫苗,如麻疹疫苗。缺乏这一弱势群体的麻疹预防数据构成了重大的临床挑战。作为回应,加拿大细胞治疗移植(CTTC)传染病工作委员会已经制定了一套常见问题,为HCT和CT接受者提供专家指导,承认证据基础有限。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Measles Outbreaks and Implications for Patients Receiving Stem Cell or Cellular Therapies in Canada: Cell Therapy Transplant Canada (CTTC) Infectious Diseases Working Committee.

Measles exposures have historically been rare since the introduction of routine vaccination programs, resulting in a lack of attention from cancer patients, hematopoietic stem cell transplant (HCT) recipients, patients receiving cellular therapy (CT) and their healthcare providers. It is essential to acknowledge the importance of vigilance in these situations. Measles herd immunity has declined significantly in North America due to rising vaccine hesitancy, resulting in outbreaks. Measles can result in severe outcomes, and its reemergence has raised alarm among patients and healthcare professionals caring for HCT/CT recipients. Patients with severe immunocompromising conditions cannot receive live-attenuated vaccines, such as the measles vaccine. The lack of data on measles prevention in this vulnerable group presents significant clinical challenges. In response, Cell Therapy Transplant Canada (CTTC) Infectious Diseases Working Committee has developed a set of frequently asked questions to provide expert guidance to HCT and CT recipients, acknowledging the limited evidence base.

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来源期刊
Current oncology
Current oncology ONCOLOGY-
CiteScore
3.30
自引率
7.70%
发文量
664
审稿时长
1 months
期刊介绍: Current Oncology is a peer-reviewed, Canadian-based and internationally respected journal. Current Oncology represents a multidisciplinary medium encompassing health care workers in the field of cancer therapy in Canada to report upon and to review progress in the management of this disease. We encourage submissions from all fields of cancer medicine, including radiation oncology, surgical oncology, medical oncology, pediatric oncology, pathology, and cancer rehabilitation and survivorship. Articles published in the journal typically contain information that is relevant directly to clinical oncology practice, and have clear potential for application to the current or future practice of cancer medicine.
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