短期暴露于细颗粒物(PM2.5)、导致特定死亡率和高危人群:一项全国时间分层病例交叉研究

IF 3.8 2区 医学 Q2 ENVIRONMENTAL SCIENCES
Geohealth Pub Date : 2025-09-26 DOI:10.1029/2024GH001214
Seoyeong Ahn, Jieun Oh, Hyewon Yun, Harin Min, Yejin Kim, Cinoo Kang, Sojin An, Ayoung Kim, Dohoon Kwon, Jinah Park, Whanhee Lee
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引用次数: 0

摘要

许多研究报告称,短期暴露于细颗粒物(PM2.5)与死亡风险有关;然而,对高危人群和地区的研究结果喜忧参半。本研究进行了一项全国性的时间分层病例交叉研究,以评估韩国(2015-2019)短期PM2.5与每个死亡原因和年龄组死亡率之间的关系。采用机器学习集成PM2.5预测模型覆盖未监测地区。我们估计了PM2.5和不符合2021年世卫组织指南(15 μg/m3)导致的额外死亡率和寿命损失年(YLL)。我们考察了生活区绿地和医疗设施的区域可达性对效果的影响。在总人口中,PM2.5与非意外原因的死亡率(OR: 1.008, 95% CI: 1.006-1.010)、循环系统疾病(1.007,95% CI: 1.003-1.011)和呼吸系统疾病(1.007,95% CI: 1.001-1.013)呈正相关。根据点估计,较年轻年龄组(0-59岁或60-69岁)的相关性通常大于较年长年龄组(70-80岁和80岁或以上),这种模式在脑血管疾病和肺炎的死亡率中也很明显。不遵守世卫组织指南导致的超额死亡率和平均寿命分别为0.80%和186,808.52年。我们的研究结果表明,制定更严格的PM2.5标准和行动计划对高风险人群和利益有益。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

Short-Term Exposure to Fine Particulate Matter (PM2.5), Cause Specific-Mortality, and High-Risk Populations: A Nationwide Time-Stratified Case-Crossover Study

Short-Term Exposure to Fine Particulate Matter (PM2.5), Cause Specific-Mortality, and High-Risk Populations: A Nationwide Time-Stratified Case-Crossover Study

Numerous studies have reported that short-term exposure to fine particulate matter (PM2.5) is associated with mortality risk; however, results on high-risk populations and regions have been mixed. This study performed a nationwide time-stratified case-crossover study to assess the association between short-term PM2.5 and mortality in South Korea (2015–2019) by each cause of death and age group. A machine-learning ensemble PM2.5 prediction model was used to cover unmonitored districts. We estimated the excess mortality and Years of Life Lost (YLL) attributable to PM2.5 and non-compliance with the 2021 WHO guidelines (>15 μg/m3). We examined the effect modifications by district-level accessibility to green spaces and medical facilities in the living sphere. In the total population, PM2.5 was positively associated with mortality for non-accidental causes (OR: 1.008 with 95% CI: 1.006–1.010), circulatory diseases (1.007, 95% CI: 1.003–1.011), and respiratory diseases (1.007, 95% CI: 1.001–1.013). Based on the point estimates, the association was generally greater in younger age groups (0–59 or 60–69 years) than in older age groups (70–80 and 80 years or older), and this pattern was pronounced in mortality for cerebrovascular diseases and pneumonia. The excess mortality fraction and YLL due to non-compliance with WHO guidelines were 0.80% and 186,808.52 years. Our findings suggest high risk populations and benefits for establishing stricter PM2.5 standards and action plans.

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来源期刊
Geohealth
Geohealth Environmental Science-Pollution
CiteScore
6.80
自引率
6.20%
发文量
124
审稿时长
19 weeks
期刊介绍: GeoHealth will publish original research, reviews, policy discussions, and commentaries that cover the growing science on the interface among the Earth, atmospheric, oceans and environmental sciences, ecology, and the agricultural and health sciences. The journal will cover a wide variety of global and local issues including the impacts of climate change on human, agricultural, and ecosystem health, air and water pollution, environmental persistence of herbicides and pesticides, radiation and health, geomedicine, and the health effects of disasters. Many of these topics and others are of critical importance in the developing world and all require bringing together leading research across multiple disciplines.
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