Seoyeong Ahn, Jieun Oh, Hyewon Yun, Harin Min, Yejin Kim, Cinoo Kang, Sojin An, Ayoung Kim, Dohoon Kwon, Jinah Park, Whanhee Lee
{"title":"短期暴露于细颗粒物(PM2.5)、导致特定死亡率和高危人群:一项全国时间分层病例交叉研究","authors":"Seoyeong Ahn, Jieun Oh, Hyewon Yun, Harin Min, Yejin Kim, Cinoo Kang, Sojin An, Ayoung Kim, Dohoon Kwon, Jinah Park, Whanhee Lee","doi":"10.1029/2024GH001214","DOIUrl":null,"url":null,"abstract":"<p>Numerous studies have reported that short-term exposure to fine particulate matter (PM<sub>2.5</sub>) is associated with mortality risk; however, results on high-risk populations and regions have been mixed. This study performed a nationwide time-stratified case-crossover study to assess the association between short-term PM<sub>2.5</sub> and mortality in South Korea (2015–2019) by each cause of death and age group. A machine-learning ensemble PM<sub>2.5</sub> prediction model was used to cover unmonitored districts. We estimated the excess mortality and Years of Life Lost (YLL) attributable to PM<sub>2.5</sub> and non-compliance with the 2021 WHO guidelines (>15 μg/m<sup>3</sup>). We examined the effect modifications by district-level accessibility to green spaces and medical facilities in the living sphere. In the total population, PM<sub>2.5</sub> was positively associated with mortality for non-accidental causes (OR: 1.008 with 95% CI: 1.006–1.010), circulatory diseases (1.007, 95% CI: 1.003–1.011), and respiratory diseases (1.007, 95% CI: 1.001–1.013). Based on the point estimates, the association was generally greater in younger age groups (0–59 or 60–69 years) than in older age groups (70–80 and 80 years or older), and this pattern was pronounced in mortality for cerebrovascular diseases and pneumonia. The excess mortality fraction and YLL due to non-compliance with WHO guidelines were 0.80% and 186,808.52 years. Our findings suggest high risk populations and benefits for establishing stricter PM<sub>2.5</sub> standards and action plans.</p>","PeriodicalId":48618,"journal":{"name":"Geohealth","volume":"9 10","pages":""},"PeriodicalIF":3.8000,"publicationDate":"2025-09-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://agupubs.onlinelibrary.wiley.com/doi/epdf/10.1029/2024GH001214","citationCount":"0","resultStr":"{\"title\":\"Short-Term Exposure to Fine Particulate Matter (PM2.5), Cause Specific-Mortality, and High-Risk Populations: A Nationwide Time-Stratified Case-Crossover Study\",\"authors\":\"Seoyeong Ahn, Jieun Oh, Hyewon Yun, Harin Min, Yejin Kim, Cinoo Kang, Sojin An, Ayoung Kim, Dohoon Kwon, Jinah Park, Whanhee Lee\",\"doi\":\"10.1029/2024GH001214\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p>Numerous studies have reported that short-term exposure to fine particulate matter (PM<sub>2.5</sub>) is associated with mortality risk; however, results on high-risk populations and regions have been mixed. This study performed a nationwide time-stratified case-crossover study to assess the association between short-term PM<sub>2.5</sub> and mortality in South Korea (2015–2019) by each cause of death and age group. A machine-learning ensemble PM<sub>2.5</sub> prediction model was used to cover unmonitored districts. We estimated the excess mortality and Years of Life Lost (YLL) attributable to PM<sub>2.5</sub> and non-compliance with the 2021 WHO guidelines (>15 μg/m<sup>3</sup>). We examined the effect modifications by district-level accessibility to green spaces and medical facilities in the living sphere. In the total population, PM<sub>2.5</sub> was positively associated with mortality for non-accidental causes (OR: 1.008 with 95% CI: 1.006–1.010), circulatory diseases (1.007, 95% CI: 1.003–1.011), and respiratory diseases (1.007, 95% CI: 1.001–1.013). Based on the point estimates, the association was generally greater in younger age groups (0–59 or 60–69 years) than in older age groups (70–80 and 80 years or older), and this pattern was pronounced in mortality for cerebrovascular diseases and pneumonia. The excess mortality fraction and YLL due to non-compliance with WHO guidelines were 0.80% and 186,808.52 years. Our findings suggest high risk populations and benefits for establishing stricter PM<sub>2.5</sub> standards and action plans.</p>\",\"PeriodicalId\":48618,\"journal\":{\"name\":\"Geohealth\",\"volume\":\"9 10\",\"pages\":\"\"},\"PeriodicalIF\":3.8000,\"publicationDate\":\"2025-09-26\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://agupubs.onlinelibrary.wiley.com/doi/epdf/10.1029/2024GH001214\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Geohealth\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://agupubs.onlinelibrary.wiley.com/doi/10.1029/2024GH001214\",\"RegionNum\":2,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q2\",\"JCRName\":\"ENVIRONMENTAL SCIENCES\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Geohealth","FirstCategoryId":"3","ListUrlMain":"https://agupubs.onlinelibrary.wiley.com/doi/10.1029/2024GH001214","RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"ENVIRONMENTAL SCIENCES","Score":null,"Total":0}
Short-Term Exposure to Fine Particulate Matter (PM2.5), Cause Specific-Mortality, and High-Risk Populations: A Nationwide Time-Stratified Case-Crossover Study
Numerous studies have reported that short-term exposure to fine particulate matter (PM2.5) is associated with mortality risk; however, results on high-risk populations and regions have been mixed. This study performed a nationwide time-stratified case-crossover study to assess the association between short-term PM2.5 and mortality in South Korea (2015–2019) by each cause of death and age group. A machine-learning ensemble PM2.5 prediction model was used to cover unmonitored districts. We estimated the excess mortality and Years of Life Lost (YLL) attributable to PM2.5 and non-compliance with the 2021 WHO guidelines (>15 μg/m3). We examined the effect modifications by district-level accessibility to green spaces and medical facilities in the living sphere. In the total population, PM2.5 was positively associated with mortality for non-accidental causes (OR: 1.008 with 95% CI: 1.006–1.010), circulatory diseases (1.007, 95% CI: 1.003–1.011), and respiratory diseases (1.007, 95% CI: 1.001–1.013). Based on the point estimates, the association was generally greater in younger age groups (0–59 or 60–69 years) than in older age groups (70–80 and 80 years or older), and this pattern was pronounced in mortality for cerebrovascular diseases and pneumonia. The excess mortality fraction and YLL due to non-compliance with WHO guidelines were 0.80% and 186,808.52 years. Our findings suggest high risk populations and benefits for establishing stricter PM2.5 standards and action plans.
期刊介绍:
GeoHealth will publish original research, reviews, policy discussions, and commentaries that cover the growing science on the interface among the Earth, atmospheric, oceans and environmental sciences, ecology, and the agricultural and health sciences. The journal will cover a wide variety of global and local issues including the impacts of climate change on human, agricultural, and ecosystem health, air and water pollution, environmental persistence of herbicides and pesticides, radiation and health, geomedicine, and the health effects of disasters. Many of these topics and others are of critical importance in the developing world and all require bringing together leading research across multiple disciplines.