Ling Yue, Jingjing Qiao, Yefang Yang, Shaowen Qie, Zhilin Mu, Yongyang Chen, Yuejiao Jia, Ming Hu
{"title":"用于沙丁胺醇分子敏感检测的锌基配位超分子传感器","authors":"Ling Yue, Jingjing Qiao, Yefang Yang, Shaowen Qie, Zhilin Mu, Yongyang Chen, Yuejiao Jia, Ming Hu","doi":"10.1002/aoc.70406","DOIUrl":null,"url":null,"abstract":"<div>\n \n <p>As a banned substance misused in doping drugs and lean meat powders, salbutamol (SAL) poses a potential threat to human health. Here, a luminescence zinc-based coordination supramolecule sensor was constructed from 2-(2′-pyridyl)benzimidazole-5-carboxylic acid (Hpbca) ligand and zinc sulfate in the self-assembly process under solvothermal conditions, namely, [Zn<sub>2</sub>(pbca)<sub>2</sub>(SO<sub>4</sub>)(H<sub>2</sub>O)<sub>3</sub>] (<b>1</b>), which could function as an efficient fluorescence probe for the detection of SAL. The single-crystal X-ray diffraction analysis reveals that complex <b>1</b> possesses distinctive binuclear building units, which are interlinked to form a three-dimensional supramolecule framework through the interactions of π···π stacking and hydrogen bonding. Complex <b>1</b> demonstrated exceptional performances with a high sensitivity (the limit of detection: 0.357 ppm), excellent anti-interference, and rapid response time. The fluorescence sensing mechanism of complex <b>1</b> toward SAL was systematically investigated through comprehensive experiments and DFT calculations. For practical implementations, we developed portable low-cost test strips by incorporating complex <b>1</b> into polymer materials, which enabled visual SAL detection through distinct color changes under the UV irradiation of 365 nm. These composite films exhibited reliable performance in recognizing SAL with the naked eye, offering promising feasibility for on-site monitoring in the fields of anti-doping and food safety.</p>\n </div>","PeriodicalId":8344,"journal":{"name":"Applied Organometallic Chemistry","volume":"39 10","pages":""},"PeriodicalIF":3.7000,"publicationDate":"2025-09-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"A Zinc-Based Coordination Supramolecule Sensor for Sensitive Detection of Salbutamol Molecule\",\"authors\":\"Ling Yue, Jingjing Qiao, Yefang Yang, Shaowen Qie, Zhilin Mu, Yongyang Chen, Yuejiao Jia, Ming Hu\",\"doi\":\"10.1002/aoc.70406\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div>\\n \\n <p>As a banned substance misused in doping drugs and lean meat powders, salbutamol (SAL) poses a potential threat to human health. Here, a luminescence zinc-based coordination supramolecule sensor was constructed from 2-(2′-pyridyl)benzimidazole-5-carboxylic acid (Hpbca) ligand and zinc sulfate in the self-assembly process under solvothermal conditions, namely, [Zn<sub>2</sub>(pbca)<sub>2</sub>(SO<sub>4</sub>)(H<sub>2</sub>O)<sub>3</sub>] (<b>1</b>), which could function as an efficient fluorescence probe for the detection of SAL. The single-crystal X-ray diffraction analysis reveals that complex <b>1</b> possesses distinctive binuclear building units, which are interlinked to form a three-dimensional supramolecule framework through the interactions of π···π stacking and hydrogen bonding. Complex <b>1</b> demonstrated exceptional performances with a high sensitivity (the limit of detection: 0.357 ppm), excellent anti-interference, and rapid response time. The fluorescence sensing mechanism of complex <b>1</b> toward SAL was systematically investigated through comprehensive experiments and DFT calculations. For practical implementations, we developed portable low-cost test strips by incorporating complex <b>1</b> into polymer materials, which enabled visual SAL detection through distinct color changes under the UV irradiation of 365 nm. These composite films exhibited reliable performance in recognizing SAL with the naked eye, offering promising feasibility for on-site monitoring in the fields of anti-doping and food safety.</p>\\n </div>\",\"PeriodicalId\":8344,\"journal\":{\"name\":\"Applied Organometallic Chemistry\",\"volume\":\"39 10\",\"pages\":\"\"},\"PeriodicalIF\":3.7000,\"publicationDate\":\"2025-09-24\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Applied Organometallic Chemistry\",\"FirstCategoryId\":\"92\",\"ListUrlMain\":\"https://onlinelibrary.wiley.com/doi/10.1002/aoc.70406\",\"RegionNum\":2,\"RegionCategory\":\"化学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q2\",\"JCRName\":\"CHEMISTRY, APPLIED\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Applied Organometallic Chemistry","FirstCategoryId":"92","ListUrlMain":"https://onlinelibrary.wiley.com/doi/10.1002/aoc.70406","RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"CHEMISTRY, APPLIED","Score":null,"Total":0}
A Zinc-Based Coordination Supramolecule Sensor for Sensitive Detection of Salbutamol Molecule
As a banned substance misused in doping drugs and lean meat powders, salbutamol (SAL) poses a potential threat to human health. Here, a luminescence zinc-based coordination supramolecule sensor was constructed from 2-(2′-pyridyl)benzimidazole-5-carboxylic acid (Hpbca) ligand and zinc sulfate in the self-assembly process under solvothermal conditions, namely, [Zn2(pbca)2(SO4)(H2O)3] (1), which could function as an efficient fluorescence probe for the detection of SAL. The single-crystal X-ray diffraction analysis reveals that complex 1 possesses distinctive binuclear building units, which are interlinked to form a three-dimensional supramolecule framework through the interactions of π···π stacking and hydrogen bonding. Complex 1 demonstrated exceptional performances with a high sensitivity (the limit of detection: 0.357 ppm), excellent anti-interference, and rapid response time. The fluorescence sensing mechanism of complex 1 toward SAL was systematically investigated through comprehensive experiments and DFT calculations. For practical implementations, we developed portable low-cost test strips by incorporating complex 1 into polymer materials, which enabled visual SAL detection through distinct color changes under the UV irradiation of 365 nm. These composite films exhibited reliable performance in recognizing SAL with the naked eye, offering promising feasibility for on-site monitoring in the fields of anti-doping and food safety.
期刊介绍:
All new compounds should be satisfactorily identified and proof of their structure given according to generally accepted standards. Structural reports, such as papers exclusively dealing with synthesis and characterization, analytical techniques, or X-ray diffraction studies of metal-organic or organometallic compounds will not be considered. The editors reserve the right to refuse without peer review any manuscript that does not comply with the aims and scope of the journal. Applied Organometallic Chemistry publishes Full Papers, Reviews, Mini Reviews and Communications of scientific research in all areas of organometallic and metal-organic chemistry involving main group metals, transition metals, lanthanides and actinides. All contributions should contain an explicit application of novel compounds, for instance in materials science, nano science, catalysis, chemical vapour deposition, metal-mediated organic synthesis, polymers, bio-organometallics, metallo-therapy, metallo-diagnostics and medicine. Reviews of books covering aspects of the fields of focus are also published.