Li Xing, Xiaobin Feng, Lin Zhang, Zheng Mo, Zhuo Yu
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Yttrium-90 Selective Internal Radiotherapy for Gastrointestinal Stromal Tumor With Liver Metastasis: A Case Report and Review
Gastrointestinal stromal tumors (GISTs), the most prevalent mesenchymal neoplasms of the gastrointestinal tract, frequently metastasize to the liver. Despite this clinical reality, there is a lack of standardized therapeutic protocols for GIST liver metastases (GISTLM). Here we present the first case of a GISTLM patient treated with Yttrium-90 (Y90) resin microsphere selective internal radiation therapy (SIRT) in China. We further reviewed the current challenges in GISTLM management and highlighted the emerging role of SIRT. By integrating case-specific insights with broader therapeutic paradigms, we aim to develop safe and effective individualized treatment strategies for GIST patients.