Depressive symptomatology and their correlates among caregivers of children and adolescents living with HIV in KwaZulu-Natal, South Africa.

Background: Few studies have examined factors linked to depressive symptomatology among caregivers of children and adolescents living with HIV (CALHIV). This study estimated prevalence of depressive symptoms and identified associated factors among caregivers of CALHIV in KwaZulu-Natal, South Africa.

Methods: We used baseline data from a cluster-randomised controlled trial of the impact of a cash transfer program and an economic empowerment intervention on health and well-being caregivers of CALHIV. Depressive symptoms were assessed using 10-item Centre for Epidemiologic Studies Depression Scale (CES-D-10), with score of ≥12 indicating presence depressive symptomatology. Correlates of depressive symptoms were identified using multilevel generalised linear models.

Results: The prevalence of depressive symptoms was 57% (95% CI: 51% - 63%). Factors associated with increased odds of depressive symptomatology were residing in peri-urban (OR = 4.80, p = 0.038), having any form of disability (OR = 8.12, p = 0.001), having existing medical condition (OR = 3.27, p = 0.009), experiencing physical abuse in the past 12 months (OR = 3.53, p = 0.020), and low social support (OR = 3.94, p = 0.005).

Conclusion: The prevalence of depressive symptoms was high among Caregivers of CALHIV. These findings highlight the need for targeted, context-specific interventions that include mental health screening for caregivers to support their mental health and well-being.