小男孩颌骨黄色肉芽肿性骨髓炎1例报告。

IF 3.5 2区 医学 Q2 GENETICS & HEREDITY
Bloch-Maier Kevin, Dridi Sophie-Myriam, Sulukdjian Arek, Ejeil Anne-Laure
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引用次数: 0

摘要

黄色肉芽肿性炎症是一种罕见的慢性炎症。它在长骨中被描述过,并且可以影响各种器官,包括唾液腺、胆囊、肾脏和胃肠道。诊断通过组织病理学显示泡沫巨噬细胞与多形核白细胞,浆细胞和多克隆淋巴细胞排列在马赛克样模式。在这里,我们提出一个16岁的男孩,一般健康状况良好,由他的正畸医生转介到布雷顿诺医院口腔外科,因为在全景x光片上偶然发现了左下颌角的无症状多面像。临床检查无显著差异。锥束计算机断层扫描显示左侧下颌角多部溶骨病变,但这不足以诊断。磁共振成像排除了血管畸形。活检显示黄色肉芽肿性骨髓炎。总之,这是第二例黄色肉芽肿性骨髓炎局部下颌骨。这突出了一个关键点:黄色肉芽肿性骨髓炎的放射图像不允许诊断;活检对于排除侵袭性或恶性肿瘤至关重要。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

Xanthogranulomatous osteomyelitis of the jaw in a young boy: a case report.

Xanthogranulomatous osteomyelitis of the jaw in a young boy: a case report.

Xanthogranulomatous osteomyelitis of the jaw in a young boy: a case report.

Xanthogranulomatous osteomyelitis of the jaw in a young boy: a case report.

Xanthogranulomatous inflammation is a rare chronic inflammatory condition. It has been described in the long bones, and can affect various organs, including the salivary glands, gallbladder, kidneys, and gastrointestinal tract. The diagnosis is made throught histopathology which reveales foamy macrophages alongside polymorphonuclear leukocytes, plasma cells, and polyclonal lymphocytes arranged in a mosaic-like pattern. Here, we present the case of a 16-year-old boy in good general health who was referred by his orthodontist to the oral surgery department at Bretonneau Hospital for an asymptomatic multipartite image of the left mandibular angle that was discovered incidentally on a panoramic radiograph. The clinical examination was unremarkable. Cone beam computed tomography revealed a multipartite osteolytic lesion of the left mandibular angle, but this that was not specific enough for a diagnosis. Magnetic resonance imaging ruled out a vascular malformation. A biopsy revealed xanthogranulomatous osteomyelitis. In summary, this is the second case of xanthogranulomatous osteomyelitis localised to the mandible. This highlights a crucial point : radiological images of xanthogranulomatous osteomyelitis do not allow for a diagnosis; a biopsy is essential to rule out an aggressive or a malignant tumor.

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来源期刊
Orphanet Journal of Rare Diseases
Orphanet Journal of Rare Diseases 医学-医学:研究与实验
CiteScore
6.30
自引率
8.10%
发文量
418
审稿时长
4-8 weeks
期刊介绍: Orphanet Journal of Rare Diseases is an open access, peer-reviewed journal that encompasses all aspects of rare diseases and orphan drugs. The journal publishes high-quality reviews on specific rare diseases. In addition, the journal may consider articles on clinical trial outcome reports, either positive or negative, and articles on public health issues in the field of rare diseases and orphan drugs. The journal does not accept case reports.
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