基于早泄诊断工具的终身早泄严重程度分级。

IF 3.4 2区 医学 Q1 ANDROLOGY
Andrology Pub Date : 2025-09-25 DOI:10.1111/andr.70124
Qianghui Zhong, Chunlin Wang, Dake Zhu, Karl H Pang, Elena Colonnello, Andrea Sansone, Qingshan Chen, Emmanuele A Jannini, Yan Zhang
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引用次数: 0

摘要

背景:早泄分级(PE)可能具有重要的价值。然而,尽管先前的研究试图实现PE的统一严重程度量表,但由于设计和方法的限制,这尚未被广泛接受。目的:通过合理的统计方法和逻辑,重新评估终身PE (LPE)患者适合进行严重程度分级的项目,建立合适的严重程度分级参考。材料与方法:采用264例男性(LPE 149例,未PE 115例)患者感知阴道内射精潜伏期(PIELT)和早泄诊断工具(PEDT)评分分析适合分类的替代项目。采用分类树和回归树来确定LPE患者不同严重程度的最佳评分区间。结果:对于PIELT < 3.5 min的LPE人群,PIELT在LPE患者严重程度的分类中没有价值。PEDT第1项和第4项与PEDT总分呈高度相关(分别为0.84和0.89),反映了LPE患者在射精控制和人际关系方面的身心影响。这些项目可以作为LPE患者严重程度的指标。因此,根据PEDT评分,可以将诊断为LPE的患者分为轻度(11-14)、中度(15-17)、重度(18-20)。这些预测和“真实”类别之间显示出实质性的一致(加权kappa 0.71)。讨论:根据三个维度评估LPE是一个被广泛接受的定义。虽然PIELT在分类上无统计学差异(p < 0.05),但射精控制和负面心理影响这两个主观维度确实预测了LPE的严重程度分级。对LPE患者的主观感受进行分级,不仅可以帮助患者自我评估病情的严重程度,还可以为进一步的治疗提供有价值的参考。结论:在3.5 min的PIELT中,根据PEDT评分,LPE的严重程度可分为重度、中度和轻度。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
The severity classification of lifelong premature ejaculation based on the premature ejaculation diagnostic tool.

Background: Grading premature ejaculation (PE) may hold significant value. However, although previous studies have attempted to achieve a uniform severity scale for PE, this has not been widely accepted since design and methodological limitations.

Objectives: In patients with lifelong PE (LPE), we re-evaluated the items suitable for severity grading and established the appropriate severity classification reference through reasonable statistical methods and logic.

Materials and methods: Patient perceived intravaginal ejaculatory latency time (PIELT) and premature ejaculation diagnostic tool (PEDT) scores from 264 men (149 with LPE and 115 without PE) were used to analyze surrogate item suitable for classification. Classification and Regression Trees were used to determine the optimal score interval for different severity levels in patients with LPE.

Results: For the LPE population with PIELT < 3.5 min, PIELT had no value in the classification of severity of LPE patients. PEDT items 1 and 4, showing high correlation (0.84 and 0.89, respectively) with PEDT total score, reflect the physical and mental effects of LPE patients in terms of ejaculatory control and interpersonal relationship. These items may serve as proxy for the severity scale of LPE patients. Hence, patients diagnosed with LPE can be classified into the following grades based on PEDT scores: mild (11-14), moderate (15-17), severe (18-20). Substantial agreement was shown between these predicted and "true" classes (weighted kappa 0.71).

Discussion: Assessing LPE according to three dimensions is a widely accepted definition. While PIELT showed no statistically significant differences in the classification (p > 0.05), the two subjective dimensions of ejaculation control and negative psychological influence did predict the severity grading of LPE. Not only can grading the subjective feelings of patients with LPE help them to self-assess the extent of the disease, but also provide a valuable reference for further treatment.

Conclusion: Within the PIELT of 3.5 min, the severity of LPE can be classified into severe, moderate, and mild categories based on the PEDT score.

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来源期刊
Andrology
Andrology ANDROLOGY-
CiteScore
9.10
自引率
6.70%
发文量
200
期刊介绍: Andrology is the study of the male reproductive system and other male gender related health issues. Andrology deals with basic and clinical aspects of the male reproductive system (gonads, endocrine and accessory organs) in all species, including the diagnosis and treatment of medical problems associated with sexual development, infertility, sexual dysfunction, sex hormone action and other urological problems. In medicine, Andrology as a specialty is a recent development, as it had previously been considered a subspecialty of urology or endocrinology
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