Abhery Das, Cecily A. Byrne, Vanessa M. Oddo, Sidra Goldman-Mellor, Sage J. Kim
{"title":"青少年和青年癌症患者的邻里剥夺与自杀","authors":"Abhery Das, Cecily A. Byrne, Vanessa M. Oddo, Sidra Goldman-Mellor, Sage J. Kim","doi":"10.1002/cam4.71247","DOIUrl":null,"url":null,"abstract":"<div>\n \n \n <section>\n \n <h3> Background</h3>\n \n <p>In 2024, approximately 84,100 adolescents and young adults (AYAs) between 15 and 39 years old received a cancer diagnosis.</p>\n </section>\n \n <section>\n \n <h3> Aims</h3>\n \n <p>Given their unique psychosocial, economic, and clinical stressors, we examined whether AYA cancer patients living in deprived neighborhoods have a higher risk of suicide when compared to those in the least deprived neighborhoods.</p>\n </section>\n \n <section>\n \n <h3> Materials & Methods</h3>\n \n <p>Our sample comprised 486,374 AYA cancer patients from the Surveillance, Epidemiology, and End Results (SEER) dataset between 2006 and 2020. We use Cox proportional hazard models to test the relation between quintiles of neighborhood deprivation, from Q1 (most deprived) to Q5 (least deprived), and survival months until suicide mortality from the time of cancer diagnosis.</p>\n </section>\n \n <section>\n \n <h3> Results</h3>\n \n <p>We find that AYA cancer patients living in more deprived neighborhoods (Q1, Q2, Q4) have a higher risk of suicide when compared to those in the least deprived neighborhoods (Q5) (Q1: HR—1.82 [1.14–2.90]; Q2: HR—1.95 [1.35–2.81]; Q4: HR—1.48 [1.05–2.07]).</p>\n </section>\n \n <section>\n \n <h3> Discussion</h3>\n \n <p>Mental health services and monitoring from treatment through survivorship may support suicide prevention efforts for young cancer patients.</p>\n </section>\n \n <section>\n \n <h3> Conclusion</h3>\n \n <p>Early identification of high-risk AYA cancer patients living in deprived areas may help target suicide prevention interventions.</p>\n </section>\n </div>","PeriodicalId":139,"journal":{"name":"Cancer Medicine","volume":"14 19","pages":""},"PeriodicalIF":3.1000,"publicationDate":"2025-09-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/cam4.71247","citationCount":"0","resultStr":"{\"title\":\"Neighborhood Deprivation and Suicide Among Adolescent and Young Adult Cancer Patients\",\"authors\":\"Abhery Das, Cecily A. Byrne, Vanessa M. Oddo, Sidra Goldman-Mellor, Sage J. Kim\",\"doi\":\"10.1002/cam4.71247\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div>\\n \\n \\n <section>\\n \\n <h3> Background</h3>\\n \\n <p>In 2024, approximately 84,100 adolescents and young adults (AYAs) between 15 and 39 years old received a cancer diagnosis.</p>\\n </section>\\n \\n <section>\\n \\n <h3> Aims</h3>\\n \\n <p>Given their unique psychosocial, economic, and clinical stressors, we examined whether AYA cancer patients living in deprived neighborhoods have a higher risk of suicide when compared to those in the least deprived neighborhoods.</p>\\n </section>\\n \\n <section>\\n \\n <h3> Materials & Methods</h3>\\n \\n <p>Our sample comprised 486,374 AYA cancer patients from the Surveillance, Epidemiology, and End Results (SEER) dataset between 2006 and 2020. We use Cox proportional hazard models to test the relation between quintiles of neighborhood deprivation, from Q1 (most deprived) to Q5 (least deprived), and survival months until suicide mortality from the time of cancer diagnosis.</p>\\n </section>\\n \\n <section>\\n \\n <h3> Results</h3>\\n \\n <p>We find that AYA cancer patients living in more deprived neighborhoods (Q1, Q2, Q4) have a higher risk of suicide when compared to those in the least deprived neighborhoods (Q5) (Q1: HR—1.82 [1.14–2.90]; Q2: HR—1.95 [1.35–2.81]; Q4: HR—1.48 [1.05–2.07]).</p>\\n </section>\\n \\n <section>\\n \\n <h3> Discussion</h3>\\n \\n <p>Mental health services and monitoring from treatment through survivorship may support suicide prevention efforts for young cancer patients.</p>\\n </section>\\n \\n <section>\\n \\n <h3> Conclusion</h3>\\n \\n <p>Early identification of high-risk AYA cancer patients living in deprived areas may help target suicide prevention interventions.</p>\\n </section>\\n </div>\",\"PeriodicalId\":139,\"journal\":{\"name\":\"Cancer Medicine\",\"volume\":\"14 19\",\"pages\":\"\"},\"PeriodicalIF\":3.1000,\"publicationDate\":\"2025-09-26\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://onlinelibrary.wiley.com/doi/epdf/10.1002/cam4.71247\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Cancer Medicine\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://onlinelibrary.wiley.com/doi/10.1002/cam4.71247\",\"RegionNum\":2,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q2\",\"JCRName\":\"ONCOLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Cancer Medicine","FirstCategoryId":"3","ListUrlMain":"https://onlinelibrary.wiley.com/doi/10.1002/cam4.71247","RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"ONCOLOGY","Score":null,"Total":0}
Neighborhood Deprivation and Suicide Among Adolescent and Young Adult Cancer Patients
Background
In 2024, approximately 84,100 adolescents and young adults (AYAs) between 15 and 39 years old received a cancer diagnosis.
Aims
Given their unique psychosocial, economic, and clinical stressors, we examined whether AYA cancer patients living in deprived neighborhoods have a higher risk of suicide when compared to those in the least deprived neighborhoods.
Materials & Methods
Our sample comprised 486,374 AYA cancer patients from the Surveillance, Epidemiology, and End Results (SEER) dataset between 2006 and 2020. We use Cox proportional hazard models to test the relation between quintiles of neighborhood deprivation, from Q1 (most deprived) to Q5 (least deprived), and survival months until suicide mortality from the time of cancer diagnosis.
Results
We find that AYA cancer patients living in more deprived neighborhoods (Q1, Q2, Q4) have a higher risk of suicide when compared to those in the least deprived neighborhoods (Q5) (Q1: HR—1.82 [1.14–2.90]; Q2: HR—1.95 [1.35–2.81]; Q4: HR—1.48 [1.05–2.07]).
Discussion
Mental health services and monitoring from treatment through survivorship may support suicide prevention efforts for young cancer patients.
Conclusion
Early identification of high-risk AYA cancer patients living in deprived areas may help target suicide prevention interventions.
期刊介绍：
Cancer Medicine is a peer-reviewed, open access, interdisciplinary journal providing rapid publication of research from global biomedical researchers across the cancer sciences. The journal will consider submissions from all oncologic specialties, including, but not limited to, the following areas:
Clinical Cancer Research
Translational research ∙ clinical trials ∙ chemotherapy ∙ radiation therapy ∙ surgical therapy ∙ clinical observations ∙ clinical guidelines ∙ genetic consultation ∙ ethical considerations
Cancer Biology:
Molecular biology ∙ cellular biology ∙ molecular genetics ∙ genomics ∙ immunology ∙ epigenetics ∙ metabolic studies ∙ proteomics ∙ cytopathology ∙ carcinogenesis ∙ drug discovery and delivery.
Cancer Prevention:
Behavioral science ∙ psychosocial studies ∙ screening ∙ nutrition ∙ epidemiology and prevention ∙ community outreach.
Bioinformatics:
Gene expressions profiles ∙ gene regulation networks ∙ genome bioinformatics ∙ pathwayanalysis ∙ prognostic biomarkers.
Cancer Medicine publishes original research articles, systematic reviews, meta-analyses, and research methods papers, along with invited editorials and commentaries. Original research papers must report well-conducted research with conclusions supported by the data presented in the paper.
求助内容：
应助结果提醒方式：
京公网安备 11010802042870号
