内分泌干扰物（EDCs）与自身免疫性甲状腺疾病（AITD）：系统的文献综述

Current Opinion in Endocrine and Metabolic Research Pub Date : 2025-09-03 DOI:10.1016/j.coemr.2025.100585

Mathilda Monaghan , Sonia Rodrigues , Shiven Sharma , Angela M. Leung , Maaike van Gerwen

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引用次数: 0

摘要

内分泌干扰化学物质（EDCs）与自身免疫性甲状腺疾病（AITD）之间的关系尚未得到很好的证实。本系统综述旨在总结现有文献，并提供最新的EDCs及其与AITD的关系综述。对美国国家医学图书馆PubMed和Scopus数据库进行检索，以确定截至2024年9月发表的相关英文文章。共有4项研究符合纳入标准。纳入的研究结果各不相同，不同EDCs与AITD的相关性从显著正相关到显著负相关不等。这篇全面的综述强调了这种关联的有限知识。除了调查个别EDC外，重要的是纳入剂量反应研究和暴露于EDC混合物。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Endocrine disruptive chemicals (EDCs) and autoimmune thyroid diseases (AITD): A systematic literature review

The association between endocrine disruptive chemicals (EDCs) and autoimmune thyroid disease (AITD) has not been well established. This systematic review aimed to summarize existing literature and provide an up-to-date overview of EDCs and their association with AITD. A search of the National Library of Medicine PubMed and Scopus databases was completed to identify relevant articles published in English through September 2024. A total of 4 studies met inclusion criteria. Results of the included studies varied, ranging from significant positive to significant negative associations with AITD for different EDCs. This comprehensive review highlights the limited knowledge of this association. Besides investigating individual EDCs, it is important to include dose–response studies and exposures to EDC mixtures.

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来源期刊

Current Opinion in Endocrine and Metabolic Research Medicine-Endocrinology, Diabetes and Metabolism

CiteScore

4.10

自引率

0.00%

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