乙烯基叠氮化物与硫酸和水氧酰基硫酰化无添加剂合成α-酮硫醇酯

IF 4.2 2区化学 Q2 CHEMISTRY, MULTIDISCIPLINARY

Chemical Communications Pub Date : 2025-09-25 DOI:10.1039/d5cc04878h

Yingjie Wang, Runmei Li, Jian Huang, Fei Jia, Zuli Wang, Wei Wei, Zi Yang, Dong Yi

{"title":"乙烯基叠氮化物与硫酸和水氧酰基硫酰化无添加剂合成α-酮硫醇酯","authors":"Yingjie Wang, Runmei Li, Jian Huang, Fei Jia, Zuli Wang, Wei Wei, Zi Yang, Dong Yi","doi":"10.1039/d5cc04878h","DOIUrl":null,"url":null,"abstract":"An additive-free strategy has been developed for the synthesis of α-keton thiol esters through direct oxyacylthiolation of vinyl azides with thioacids and water. The C-S and C=O bonds were formed in a one-pot operation via a radical reaction pathway. A number of α-keton thiol esters could be efficiently obtained in good yields with broad substrate scope and good functional group tolerance.","PeriodicalId":67,"journal":{"name":"Chemical Communications","volume":"30 1","pages":""},"PeriodicalIF":4.2000,"publicationDate":"2025-09-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Additive-free synthesis of α-keton thiol esters via oxyacylthiolation of vinyl azides with thioacids and water\",\"authors\":\"Yingjie Wang, Runmei Li, Jian Huang, Fei Jia, Zuli Wang, Wei Wei, Zi Yang, Dong Yi\",\"doi\":\"10.1039/d5cc04878h\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"An additive-free strategy has been developed for the synthesis of α-keton thiol esters through direct oxyacylthiolation of vinyl azides with thioacids and water. The C-S and C=O bonds were formed in a one-pot operation via a radical reaction pathway. A number of α-keton thiol esters could be efficiently obtained in good yields with broad substrate scope and good functional group tolerance.\",\"PeriodicalId\":67,\"journal\":{\"name\":\"Chemical Communications\",\"volume\":\"30 1\",\"pages\":\"\"},\"PeriodicalIF\":4.2000,\"publicationDate\":\"2025-09-25\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Chemical Communications\",\"FirstCategoryId\":\"92\",\"ListUrlMain\":\"https://doi.org/10.1039/d5cc04878h\",\"RegionNum\":2,\"RegionCategory\":\"化学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q2\",\"JCRName\":\"CHEMISTRY, MULTIDISCIPLINARY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Chemical Communications","FirstCategoryId":"92","ListUrlMain":"https://doi.org/10.1039/d5cc04878h","RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"CHEMISTRY, MULTIDISCIPLINARY","Score":null,"Total":0}

引用次数: 0

摘要

提出了一种无添加剂合成α-酮硫醇酯的方法，即用硫代酸和水直接氧酰基硫代化叠氮化乙烯基。C- s键和C=O键通过自由基反应途径在一锅操作中形成。该方法能高效、高产地合成α-酮硫醇酯，底物范围广，官能团耐受性好。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

查看原文本刊更多论文

Additive-free synthesis of α-keton thiol esters via oxyacylthiolation of vinyl azides with thioacids and water

An additive-free strategy has been developed for the synthesis of α-keton thiol esters through direct oxyacylthiolation of vinyl azides with thioacids and water. The C-S and C=O bonds were formed in a one-pot operation via a radical reaction pathway. A number of α-keton thiol esters could be efficiently obtained in good yields with broad substrate scope and good functional group tolerance.

求助全文

通过发布文献求助，成功后即可免费获取论文全文。去求助

来源期刊

Chemical Communications 化学-化学综合

CiteScore

8.60

自引率

4.10%

发文量

2705

审稿时长

1.4 months

期刊介绍： ChemComm (Chemical Communications) is renowned as the fastest publisher of articles providing information on new avenues of research, drawn from all the world''s major areas of chemical research.