The association of ınsomnia with fatigue and mood in postmenopausal osteoporosis.

Objective: The aim of the study was to investigate the prevalence of insomnia in postmenopausal osteoporotic women. It also evaluated the relationship between insomnia, fatigue, and mood disorders.

Methods: This cross-sectional study was conducted with 200 postmenopausal osteoporotic women aged 50-75 years. Insomnia severity was assessed using the Insomnia Severity Index, while fatigue and mood disorders were measured using the Fatigue Severity Scale and the Hospital Anxiety and Depression Scale, respectively. The participants were divided into two groups based on the Insomnia Severity Index scores, using a cutoff of 15. We then analyzed the clinical characteristics of these two groups, focusing on the relationship between insomnia severity and factors such as fatigue, anxiety, depression, and bone mineral density.

Results: Among the participants, 20.5% were clinically diagnosed with insomnia (Insomnia Severity Index≥15). Sleep initiation difficulties were reported by 73.5%, sleep maintenance difficulties by 57.5%, and early awakening by 45%. Insomnia severity was significantly correlated with higher levels of fatigue (r=0.342, p<0.001), depression (r=0.297, p<0.001), and anxiety (r=0.323, p<0.001). There was no significant correlation between insomnia and bone mineral density or T-scores.

Conclusion: Insomnia is common in postmenopausal osteoporotic women and is closely linked to higher fatigue, anxiety, and depression levels. Early detection and management of insomnia in this population are essential to reduce fall risk and prevent fractures.