Michael O Akon, Rachel M Kenney, Nathan A Everson, Sydney VanDorf, Geehan Suleyman, Robert J Tibbetts, Anita B Shallal, Michael P Veve
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A little nudge goes a long way: assessing the impact of a microbiology nudge comment on narrow-spectrum antibiotic use in uncomplicated Streptococcus pneumoniae bloodstream infections.
Narrow-spectrum antibiotic prescribing (ampicillin IV or penicillin IV) was compared before and after implementing an interpretive microbiology comment for uncomplicated Streptococcus pneumoniae bloodstream infections. The postintervention group was associated with 4-fold increased odds of de-escalation to narrow-spectrum antibiotics (adjusted odds ratio, 4.66; 95% confidence interval, 1.97-11.00).
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