Wiwiek Tyasningsih, Aswin Rafif Khairullah, John Yew Huat Tang, Mustofa Helmi Effendi, Saifur Rehman, Ilma Fauziah Ma'ruf, Bantari Wisynu Kusuma Wardhani, Ikechukwu Benjamin Moses, Budiastuti Budiastuti, Kartika Afrida Fauzia, Riza Zainuddin Ahmad, Ima Fauziah, Muhammad Khaliim Jati Kusala, Bima Putra Pratama, Dea Anita Ariani Kurniasih, Syahputra Wibowo
{"title":"黑腿病:一种病因不明的致命疾病。","authors":"Wiwiek Tyasningsih, Aswin Rafif Khairullah, John Yew Huat Tang, Mustofa Helmi Effendi, Saifur Rehman, Ilma Fauziah Ma'ruf, Bantari Wisynu Kusuma Wardhani, Ikechukwu Benjamin Moses, Budiastuti Budiastuti, Kartika Afrida Fauzia, Riza Zainuddin Ahmad, Ima Fauziah, Muhammad Khaliim Jati Kusala, Bima Putra Pratama, Dea Anita Ariani Kurniasih, Syahputra Wibowo","doi":"10.5455/OVJ.2025.v15.i6.7","DOIUrl":null,"url":null,"abstract":"<p><p>Blackleg is an infectious disease that mainly affects cattle and rarely affects other ruminants. It is characterized by hemorrhagic blackleg myositis. <i>Clostridium chauvoei</i> is a highly pathogenic anaerobic, endospore-forming Gram- positive bacteria that causes blackleg disease. Blackleg disease was first reported in 1870, but the causative bacterium <i>C. chauvoei</i> was not described until 1887. Clostridium chauvoei is found in grassland, fresh water, silage, soil, and the excrement of healthy animals. Cattle intestines and pasture soil have both been found to contain <i>C. chauvoei</i> spores, suggesting that the infection is contracted by ingesting the spores. Significant lesions are less common in the heart and more common in the skeletal muscle. Anaerobic culture, polymerase chain reaction, immunodetection using fluorescent antibody tests, and immunohistochemistry are methods for identifying bacteria. The production of gas in animal tissues, known as emphysematous swelling, is a hallmark of blackleg illness. Swelling usually affects big muscles including the neck, shoulders, thighs, and hips. Most incidences of blackleg illness in cattle occur during the warmer months of the year, and the disease typically manifests seasonally. Penicillin treatment and surgical removal of the lesions, including fasciotomy, are recommended for infected animals that are not in danger of death. Vaccination is a crucial part of the health management of many livestock production enterprises and can prevent blackleg illness. Blackleg disease can be controlled by destroying the carcass and burning the top layer of soil to eradicate any remaining spores.</p>","PeriodicalId":19531,"journal":{"name":"Open Veterinary Journal","volume":"15 6","pages":"2343-2354"},"PeriodicalIF":1.0000,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12451119/pdf/","citationCount":"0","resultStr":"{\"title\":\"Blackleg: A deadly disease with a hidden cause.\",\"authors\":\"Wiwiek Tyasningsih, Aswin Rafif Khairullah, John Yew Huat Tang, Mustofa Helmi Effendi, Saifur Rehman, Ilma Fauziah Ma'ruf, Bantari Wisynu Kusuma Wardhani, Ikechukwu Benjamin Moses, Budiastuti Budiastuti, Kartika Afrida Fauzia, Riza Zainuddin Ahmad, Ima Fauziah, Muhammad Khaliim Jati Kusala, Bima Putra Pratama, Dea Anita Ariani Kurniasih, Syahputra Wibowo\",\"doi\":\"10.5455/OVJ.2025.v15.i6.7\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>Blackleg is an infectious disease that mainly affects cattle and rarely affects other ruminants. It is characterized by hemorrhagic blackleg myositis. <i>Clostridium chauvoei</i> is a highly pathogenic anaerobic, endospore-forming Gram- positive bacteria that causes blackleg disease. Blackleg disease was first reported in 1870, but the causative bacterium <i>C. chauvoei</i> was not described until 1887. Clostridium chauvoei is found in grassland, fresh water, silage, soil, and the excrement of healthy animals. Cattle intestines and pasture soil have both been found to contain <i>C. chauvoei</i> spores, suggesting that the infection is contracted by ingesting the spores. Significant lesions are less common in the heart and more common in the skeletal muscle. Anaerobic culture, polymerase chain reaction, immunodetection using fluorescent antibody tests, and immunohistochemistry are methods for identifying bacteria. The production of gas in animal tissues, known as emphysematous swelling, is a hallmark of blackleg illness. Swelling usually affects big muscles including the neck, shoulders, thighs, and hips. Most incidences of blackleg illness in cattle occur during the warmer months of the year, and the disease typically manifests seasonally. Penicillin treatment and surgical removal of the lesions, including fasciotomy, are recommended for infected animals that are not in danger of death. Vaccination is a crucial part of the health management of many livestock production enterprises and can prevent blackleg illness. Blackleg disease can be controlled by destroying the carcass and burning the top layer of soil to eradicate any remaining spores.</p>\",\"PeriodicalId\":19531,\"journal\":{\"name\":\"Open Veterinary Journal\",\"volume\":\"15 6\",\"pages\":\"2343-2354\"},\"PeriodicalIF\":1.0000,\"publicationDate\":\"2025-06-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12451119/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Open Veterinary Journal\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.5455/OVJ.2025.v15.i6.7\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2025/6/30 0:00:00\",\"PubModel\":\"Epub\",\"JCR\":\"Q3\",\"JCRName\":\"VETERINARY SCIENCES\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Open Veterinary Journal","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.5455/OVJ.2025.v15.i6.7","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2025/6/30 0:00:00","PubModel":"Epub","JCR":"Q3","JCRName":"VETERINARY SCIENCES","Score":null,"Total":0}
Blackleg is an infectious disease that mainly affects cattle and rarely affects other ruminants. It is characterized by hemorrhagic blackleg myositis. Clostridium chauvoei is a highly pathogenic anaerobic, endospore-forming Gram- positive bacteria that causes blackleg disease. Blackleg disease was first reported in 1870, but the causative bacterium C. chauvoei was not described until 1887. Clostridium chauvoei is found in grassland, fresh water, silage, soil, and the excrement of healthy animals. Cattle intestines and pasture soil have both been found to contain C. chauvoei spores, suggesting that the infection is contracted by ingesting the spores. Significant lesions are less common in the heart and more common in the skeletal muscle. Anaerobic culture, polymerase chain reaction, immunodetection using fluorescent antibody tests, and immunohistochemistry are methods for identifying bacteria. The production of gas in animal tissues, known as emphysematous swelling, is a hallmark of blackleg illness. Swelling usually affects big muscles including the neck, shoulders, thighs, and hips. Most incidences of blackleg illness in cattle occur during the warmer months of the year, and the disease typically manifests seasonally. Penicillin treatment and surgical removal of the lesions, including fasciotomy, are recommended for infected animals that are not in danger of death. Vaccination is a crucial part of the health management of many livestock production enterprises and can prevent blackleg illness. Blackleg disease can be controlled by destroying the carcass and burning the top layer of soil to eradicate any remaining spores.
期刊介绍:
Open Veterinary Journal is a peer-reviewed international open access online and printed journal that publishes high-quality original research articles. reviews, short communications and case reports dedicated to all aspects of veterinary sciences and its related subjects. Research areas include the following: Infectious diseases of zoonotic/food-borne importance, applied biochemistry, parasitology, endocrinology, microbiology, immunology, pathology, pharmacology, physiology, epidemiology, molecular biology, immunogenetics, surgery, ophthalmology, dermatology, oncology and animal reproduction. All papers are peer-reviewed. Moreover, with the presence of well-qualified group of international referees, the process of publication will be done meticulously and to the highest standards.