{"title":"微流体和场辅助3D打印:利用流体控制,电动现象和其他物理领域来推进增材制造。","authors":"Guillermo Ramirez-Alvarado, Gongchen Sun","doi":"10.1002/elps.70041","DOIUrl":null,"url":null,"abstract":"<p><p>Three-dimensional (3D) printing has revolutionized manufacturing by enabling the rapid fabrication of complex structures, yet conventional 3D techniques remain constrained by inherent limitations in resolution, speed, and multi-material integration. To address these challenges, emerging approaches such as microfluidic-assisted and field-assisted additive manufacturing have been developed to enhance the capabilities and versatility of the method. Microfluidic-assisted 3D printing leverages controlled flow patterns for material deposition and control, material gradient formation, and advanced polymerization processes. Field-assisted methods, including electric-, acoustic-, and interface-assisted approaches, directly manipulate materials during printing to enable advanced functionalities and material properties. This review summarizes the latest advancements in microfluidic- and field-assisted 3D printing, highlighting their unique advantage in overcoming current 3D printing limitations and their potential to drive innovation in applications ranging from biomedical devices to functional materials development.</p>","PeriodicalId":11596,"journal":{"name":"ELECTROPHORESIS","volume":" ","pages":""},"PeriodicalIF":2.5000,"publicationDate":"2025-09-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Microfluidic- and Field-Assisted 3D Printing: Leveraging Fluidic Control, Electrokinetic Phenomena, and Other Physical Fields to Advance Additive Manufacturing.\",\"authors\":\"Guillermo Ramirez-Alvarado, Gongchen Sun\",\"doi\":\"10.1002/elps.70041\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>Three-dimensional (3D) printing has revolutionized manufacturing by enabling the rapid fabrication of complex structures, yet conventional 3D techniques remain constrained by inherent limitations in resolution, speed, and multi-material integration. To address these challenges, emerging approaches such as microfluidic-assisted and field-assisted additive manufacturing have been developed to enhance the capabilities and versatility of the method. Microfluidic-assisted 3D printing leverages controlled flow patterns for material deposition and control, material gradient formation, and advanced polymerization processes. Field-assisted methods, including electric-, acoustic-, and interface-assisted approaches, directly manipulate materials during printing to enable advanced functionalities and material properties. This review summarizes the latest advancements in microfluidic- and field-assisted 3D printing, highlighting their unique advantage in overcoming current 3D printing limitations and their potential to drive innovation in applications ranging from biomedical devices to functional materials development.</p>\",\"PeriodicalId\":11596,\"journal\":{\"name\":\"ELECTROPHORESIS\",\"volume\":\" \",\"pages\":\"\"},\"PeriodicalIF\":2.5000,\"publicationDate\":\"2025-09-23\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"ELECTROPHORESIS\",\"FirstCategoryId\":\"99\",\"ListUrlMain\":\"https://doi.org/10.1002/elps.70041\",\"RegionNum\":3,\"RegionCategory\":\"生物学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q2\",\"JCRName\":\"BIOCHEMICAL RESEARCH METHODS\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"ELECTROPHORESIS","FirstCategoryId":"99","ListUrlMain":"https://doi.org/10.1002/elps.70041","RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"BIOCHEMICAL RESEARCH METHODS","Score":null,"Total":0}
Microfluidic- and Field-Assisted 3D Printing: Leveraging Fluidic Control, Electrokinetic Phenomena, and Other Physical Fields to Advance Additive Manufacturing.
Three-dimensional (3D) printing has revolutionized manufacturing by enabling the rapid fabrication of complex structures, yet conventional 3D techniques remain constrained by inherent limitations in resolution, speed, and multi-material integration. To address these challenges, emerging approaches such as microfluidic-assisted and field-assisted additive manufacturing have been developed to enhance the capabilities and versatility of the method. Microfluidic-assisted 3D printing leverages controlled flow patterns for material deposition and control, material gradient formation, and advanced polymerization processes. Field-assisted methods, including electric-, acoustic-, and interface-assisted approaches, directly manipulate materials during printing to enable advanced functionalities and material properties. This review summarizes the latest advancements in microfluidic- and field-assisted 3D printing, highlighting their unique advantage in overcoming current 3D printing limitations and their potential to drive innovation in applications ranging from biomedical devices to functional materials development.
期刊介绍:
ELECTROPHORESIS is an international journal that publishes original manuscripts on all aspects of electrophoresis, and liquid phase separations (e.g., HPLC, micro- and nano-LC, UHPLC, micro- and nano-fluidics, liquid-phase micro-extractions, etc.).
Topics include new or improved analytical and preparative methods, sample preparation, development of theory, and innovative applications of electrophoretic and liquid phase separations methods in the study of nucleic acids, proteins, carbohydrates natural products, pharmaceuticals, food analysis, environmental species and other compounds of importance to the life sciences.
Papers in the areas of microfluidics and proteomics, which are not limited to electrophoresis-based methods, will also be accepted for publication. Contributions focused on hyphenated and omics techniques are also of interest. Proteomics is within the scope, if related to its fundamentals and new technical approaches. Proteomics applications are only considered in particular cases.
Papers describing the application of standard electrophoretic methods will not be considered.
Papers on nanoanalysis intended for publication in ELECTROPHORESIS should focus on one or more of the following topics:
• Nanoscale electrokinetics and phenomena related to electric double layer and/or confinement in nano-sized geometry
• Single cell and subcellular analysis
• Nanosensors and ultrasensitive detection aspects (e.g., involving quantum dots, "nanoelectrodes" or nanospray MS)
• Nanoscale/nanopore DNA sequencing (next generation sequencing)
• Micro- and nanoscale sample preparation
• Nanoparticles and cells analyses by dielectrophoresis
• Separation-based analysis using nanoparticles, nanotubes and nanowires.