Çağatay Tunca, Fatih Cihat Büyükbaş, Alperen Taş, Veysel Ozan Tanık, Süleyman Barutçu, Bülent Özlek
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During hospitalization (maximum 12 days), 106 patients (11.0%) died. Non-survivors were significantly older (69.1 vs 58.9 years, <i>P</i> < .001) and more frequently female (36.8 vs 19%, <i>P</i> < .001). Independent predictors included advanced age, low diastolic blood pressure, higher Killip class, reduced left ventricular ejection fraction, elevated creatinine and troponin levels, and high OPS values (hazard ratio: 3.032; 95% confidence interval [CI]: 2.003-4.102; <i>P</i> < .001). An OPS threshold of 1.5 yielded 94% sensitivity and 74% specificity (95% CI: 0.859-0.937; <i>P</i> < .001), with mortality rates of 3.7%, 4.2%, 17.1%, and 59.1% across OPS categories (<i>P</i> < .001). Incorporating OPS with conventional risk factors may enhance the risk stratification of NSTEMI.</p>","PeriodicalId":8264,"journal":{"name":"Angiology","volume":" ","pages":"33197251370103"},"PeriodicalIF":2.2000,"publicationDate":"2025-09-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"The Osaka Prognostic Score Predicts All-Cause in-Hospital Mortality in Patients With Non-ST-Elevation Myocardial Infarction Undergoing Early Percutaneous Coronary Intervention.\",\"authors\":\"Çağatay Tunca, Fatih Cihat Büyükbaş, Alperen Taş, Veysel Ozan Tanık, Süleyman Barutçu, Bülent Özlek\",\"doi\":\"10.1177/00033197251370103\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>The Osaka Prognostic Score (OPS) is a composite index reflecting systemic inflammation and nutritional status, derived from C-reactive protein, albumin, and lymphocyte count. This retrospective study evaluated the association between OPS and all-cause in-hospital mortality in 959 patients with non-ST-elevation myocardial infarction (NSTEMI) undergoing early percutaneous coronary intervention from September 2022 to November 2024. Patients were stratified into 4 groups based on OPS (0-3), with all-cause in-hospital mortality as the primary endpoint. Cox proportional hazards modeling was used to identify independent predictors of mortality, and receiver operating characteristic analysis assessed the prognostic performance of OPS. During hospitalization (maximum 12 days), 106 patients (11.0%) died. Non-survivors were significantly older (69.1 vs 58.9 years, <i>P</i> < .001) and more frequently female (36.8 vs 19%, <i>P</i> < .001). Independent predictors included advanced age, low diastolic blood pressure, higher Killip class, reduced left ventricular ejection fraction, elevated creatinine and troponin levels, and high OPS values (hazard ratio: 3.032; 95% confidence interval [CI]: 2.003-4.102; <i>P</i> < .001). An OPS threshold of 1.5 yielded 94% sensitivity and 74% specificity (95% CI: 0.859-0.937; <i>P</i> < .001), with mortality rates of 3.7%, 4.2%, 17.1%, and 59.1% across OPS categories (<i>P</i> < .001). 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引用次数: 0
摘要
大阪预后评分(OPS)是反映全身炎症和营养状况的综合指数,由c反应蛋白、白蛋白和淋巴细胞计数得出。这项回顾性研究评估了从2022年9月至2024年11月接受早期经皮冠状动脉介入治疗的959例非st段抬高型心肌梗死(NSTEMI)患者的OPS与全因住院死亡率之间的关系。根据OPS(0-3)将患者分为4组,以院内全因死亡率为主要终点。采用Cox比例风险模型确定死亡率的独立预测因素,并通过受试者操作特征分析评估OPS的预后表现。在住院期间(最多12天),106例患者(11.0%)死亡。非幸存者明显变老(69.1岁vs 58.9岁,P P P P P
The Osaka Prognostic Score Predicts All-Cause in-Hospital Mortality in Patients With Non-ST-Elevation Myocardial Infarction Undergoing Early Percutaneous Coronary Intervention.
The Osaka Prognostic Score (OPS) is a composite index reflecting systemic inflammation and nutritional status, derived from C-reactive protein, albumin, and lymphocyte count. This retrospective study evaluated the association between OPS and all-cause in-hospital mortality in 959 patients with non-ST-elevation myocardial infarction (NSTEMI) undergoing early percutaneous coronary intervention from September 2022 to November 2024. Patients were stratified into 4 groups based on OPS (0-3), with all-cause in-hospital mortality as the primary endpoint. Cox proportional hazards modeling was used to identify independent predictors of mortality, and receiver operating characteristic analysis assessed the prognostic performance of OPS. During hospitalization (maximum 12 days), 106 patients (11.0%) died. Non-survivors were significantly older (69.1 vs 58.9 years, P < .001) and more frequently female (36.8 vs 19%, P < .001). Independent predictors included advanced age, low diastolic blood pressure, higher Killip class, reduced left ventricular ejection fraction, elevated creatinine and troponin levels, and high OPS values (hazard ratio: 3.032; 95% confidence interval [CI]: 2.003-4.102; P < .001). An OPS threshold of 1.5 yielded 94% sensitivity and 74% specificity (95% CI: 0.859-0.937; P < .001), with mortality rates of 3.7%, 4.2%, 17.1%, and 59.1% across OPS categories (P < .001). Incorporating OPS with conventional risk factors may enhance the risk stratification of NSTEMI.
期刊介绍:
A presentation of original, peer-reviewed original articles, review and case reports relative to all phases of all vascular diseases, Angiology (ANG) offers more than a typical cardiology journal. With approximately 1000 pages per year covering diagnostic methods, therapeutic approaches, and clinical and laboratory research, ANG is among the most informative publications in the field of peripheral vascular and cardiovascular diseases. This journal is a member of the Committee on Publication Ethics (COPE). Average time from submission to first decision: 13 days