乙烯基醚的电氧化烷氧基-巯基化

IF 4 2区化学 Q2 CHEMISTRY, APPLIED

Advanced Synthesis & Catalysis Pub Date : 2025-09-23 DOI:10.1002/adsc.70132

Zhuang Wang, Rongxin Yang, Yuxiu Liu, Hongjian Song, Qingmin Wang

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引用次数: 0

摘要

在无氧化剂和无金属的条件下，采用非挥发性二硫化物作为原子经济的芳硫源，研究了乙烯基醚烷氧基化硫基化的电氧化方案。采用4-（三氟甲基）吡啶作为碱添加剂抑制副反应，提高收率。具有不同结构和官能团的广泛底物与该协议兼容。机理实验表明，该反应的机理是在阳极处生成一个芳基硫自由基作为关键中间体。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

Electro-Oxidative Alkoxylation-Thiolation of Vinyl Ethers

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Electro-Oxidative Alkoxylation-Thiolation of Vinyl Ethers

An electro-oxidative protocol for the alkoxylation-thiolation of vinyl ethers is developed, employing nonvolatile diaryl disulfides as atom-economical arylthio sources under oxidant-free and metal-free conditions. 4-(Trifluoromethyl)pyridine is used as a base additive to suppress side reactions and improve the yield. A wide range of substrates with diverse structures and functional groups are compatible with this protocol. Mechanism experiments show that the reaction involves a mechanism in which an arylthio radical is generated at the anode as the key intermediate.

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来源期刊

Advanced Synthesis & Catalysis 化学-应用化学

CiteScore

9.40

自引率

7.40%

发文量

447

审稿时长

1.8 months

期刊介绍： Advanced Synthesis & Catalysis (ASC) is the leading primary journal in organic, organometallic, and applied chemistry. The high impact of ASC can be attributed to the unique focus of the journal, which publishes exciting new results from academic and industrial labs on efficient, practical, and environmentally friendly organic synthesis. While homogeneous, heterogeneous, organic, and enzyme catalysis are key technologies to achieve green synthesis, significant contributions to the same goal by synthesis design, reaction techniques, flow chemistry, and continuous processing, multiphase catalysis, green solvents, catalyst immobilization, and recycling, separation science, and process development are also featured in ASC. The Aims and Scope can be found in the Notice to Authors or on the first page of the table of contents in every issue.