对“发现具有选择性有效抗病毒和抗增殖活性的新型芳乙基三唑核糖核苷”的更正

IF 6.8 1区医学 Q1 CHEMISTRY, MEDICINAL

Journal of Medicinal Chemistry Pub Date : 2025-09-23 DOI:10.1021/acs.jmedchem.5c02591

Jinqiao Wan, Yi Xia, Yang Liu, Menghua Wang, Palma Rocchi, Jianhua Yao, Fanqi Qu, Johan Neyts, Juan L. Iovanna, Ling Peng

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引用次数: 0

摘要

在图7中，肿瘤体积计算错误。更正后的图7如下所示。该误差不影响结果的统计显著性或研究结论。作者对这个错误感到遗憾。图7。3f治疗对体内耐药MiaPaCa-2肿瘤生长的影响。随机选取携带100 mm3 MiaPaCa-2肿瘤的裸鼠，给予3f治疗，不给予治疗作为对照。3f每3天腹腔注射150 (mg/kg)/只，连续注射4周，每周测量肿瘤体积1次。所有结果均以均数±SE （n = 5）表示：分，分析平均值；Bars，标准误差；经Student 's t检验，*，与对照组差异（p≤0.05），**，与对照组差异（p≤0.01）。这篇文章尚未被其他出版物引用。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

Correction to “Discovery of Novel Arylethynyltriazole Ribonucleosides with Selective and Effective Antiviral and Antiproliferative Activity”

查看原文本刊更多论文

Correction to “Discovery of Novel Arylethynyltriazole Ribonucleosides with Selective and Effective Antiviral and Antiproliferative Activity”

In Figure 7, tumor volumes were incorrectly calculated. The corrected Figure 7 is provided below in this Addition/Correction. This error does not affect the statistical significance of the results or the conclusions of the study. The authors regret this error. Figure 7. Effect of 3f treatment on chemoresistant MiaPaCa-2 tumor growth in vivo. Nude mice bearing MiaPaCa-2 tumors of 100 mm³ were randomly selected for treatment with 3f and no treatment as control. 3f was injected intraperitoneally (150 (mg/kg)/mice) every 3 days for 4 weeks and tumor volume measured once a week. All of the results were expressed as the mean ± SE (n = 5): points, mean values of analysis; bars, standard errors; *, differing from control (p ≤ 0.05), **, differing from control (p ≤ 0.01) by Student’s t test. This article has not yet been cited by other publications.

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来源期刊

Journal of Medicinal Chemistry 医学-医药化学

CiteScore

4.00

自引率

11.00%

发文量

804

审稿时长

1.9 months

期刊介绍： The Journal of Medicinal Chemistry is a prestigious biweekly peer-reviewed publication that focuses on the multifaceted field of medicinal chemistry. Since its inception in 1959 as the Journal of Medicinal and Pharmaceutical Chemistry, it has evolved to become a cornerstone in the dissemination of research findings related to the design, synthesis, and development of therapeutic agents. The Journal of Medicinal Chemistry is recognized for its significant impact in the scientific community, as evidenced by its 2022 impact factor of 7.3. This metric reflects the journal's influence and the importance of its content in shaping the future of drug discovery and development. The journal serves as a vital resource for chemists, pharmacologists, and other researchers interested in the molecular mechanisms of drug action and the optimization of therapeutic compounds.