更正“新型三唑核苷下调热休克蛋白27诱导耐药胰腺癌有效抗癌活性”

IF 6.8 1区医学 Q1 CHEMISTRY, MEDICINAL

Journal of Medicinal Chemistry Pub Date : 2025-09-24 DOI:10.1021/acs.jmedchem.5c02592

Yi Xia, Yang Liu, Jinqiao Wan, Menghua Wang, Palma Rocchi, Fanqi Qu, Juan L. Iovanna, Ling Peng

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引用次数: 0

摘要

在图9A中，肿瘤体积计算错误。更正后的图9A载于本补充/更正下文。该误差不影响结果的统计显著性或研究结论。我们为这个错误道歉。图9。(A) 3e治疗对体内耐药MiaPaCa-2肿瘤生长的影响。随机选择携带100 mm3的MiaPaCa-2肿瘤的裸鼠，用3e治疗，不治疗作为对照组。每3天腹腔注射3e （150 mg/kg/只），连续5周，每周测量1次肿瘤体积。所有结果均以均数±SE表示（n = 8）：点为分析的平均值；条形是标准误差；经Student 's t检验，*，与对照组差异（p≤0.05），**，与对照组差异（p≤0.01）。这篇文章尚未被其他出版物引用。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

Correction to “Novel Triazole Ribonucleoside Down-Regulates Heat Shock Protein 27 and Induces Potent Anticancer Activity on Drug-Resistant Pancreatic Cancer”

查看原文本刊更多论文

Correction to “Novel Triazole Ribonucleoside Down-Regulates Heat Shock Protein 27 and Induces Potent Anticancer Activity on Drug-Resistant Pancreatic Cancer”

In Figure 9A, tumor volumes were incorrectly calculated. The corrected Figure 9A is provided below in this Addition/Correction. This error does not affect the statistical significance of the results or the conclusions of the study. We apologize for this error. Figure 9. (A) Effect of 3e treatment on drug-resistant MiaPaCa-2 tumor growth in vivo. Nude mice bearing MiaPaCa-2 tumors of 100 mm³ were randomly selected for treatment with 3e and no treatment as control. 3e was injected intraperitoneally (150 mg/kg/mice) every 3 days for 5 weeks, and tumor volume was measured once a week. All of the results were expressed as the mean ± SE (n = 8): points are the means values of analysis; bars are the standard errors; *, differing from control (p ≤ 0.05), **, differing from control (p ≤ 0.01) by Student’s t test. This article has not yet been cited by other publications.

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来源期刊

Journal of Medicinal Chemistry 医学-医药化学

CiteScore

4.00

自引率

11.00%

发文量

804

审稿时长

1.9 months

期刊介绍： The Journal of Medicinal Chemistry is a prestigious biweekly peer-reviewed publication that focuses on the multifaceted field of medicinal chemistry. Since its inception in 1959 as the Journal of Medicinal and Pharmaceutical Chemistry, it has evolved to become a cornerstone in the dissemination of research findings related to the design, synthesis, and development of therapeutic agents. The Journal of Medicinal Chemistry is recognized for its significant impact in the scientific community, as evidenced by its 2022 impact factor of 7.3. This metric reflects the journal's influence and the importance of its content in shaping the future of drug discovery and development. The journal serves as a vital resource for chemists, pharmacologists, and other researchers interested in the molecular mechanisms of drug action and the optimization of therapeutic compounds.