蜗牛:汗液感应钉,用于不显眼的,可穿戴的微流体汗液监测从远端指骨背。

IF 5.4 2区 工程技术 Q1 BIOCHEMICAL RESEARCH METHODS
Lab on a Chip Pub Date : 2025-09-24 DOI:10.1039/d5lc00586h
Noelle Davis,Pooja Mehta,Amanda Kang,Liam Gillan,Jussi Hiltunen,Ali Javey
{"title":"蜗牛:汗液感应钉,用于不显眼的,可穿戴的微流体汗液监测从远端指骨背。","authors":"Noelle Davis,Pooja Mehta,Amanda Kang,Liam Gillan,Jussi Hiltunen,Ali Javey","doi":"10.1039/d5lc00586h","DOIUrl":null,"url":null,"abstract":"We present a fingernail-mounted microfluidic sweat sensor, the sNail, that leverages the anatomical and mechanical advantages of the nail plate and adjacent dorsal finger skin-regions that are uniquely stiff and stable yet underutilized for wearable biosensing. In contrast to fully soft, skin-mounted sensors, our device exploits the rigidity of the nail to host microfluidics that remain stable under typical daily finger motion. The platform incorporates a hydrogel-filled sweat collection well and stretchable thermoplastic polyurethane (TPU) microfluidics, fabricated via scalable laserjet printing and laser cutting. We demonstrate frequent sweat rate monitoring across multiple fingers and subjects during activities ranging from walking to typing, and capture dynamic changes in sweat rate associated with both physical exertion and psychological stress. This nail-mounted approach enables unobtrusive, informative sweat biosensing, paving the way for broader adoption in everyday settings.","PeriodicalId":85,"journal":{"name":"Lab on a Chip","volume":"13 1","pages":""},"PeriodicalIF":5.4000,"publicationDate":"2025-09-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"sNails: sweat-sensing nails for unobtrusive, wearable microfluidic sweat monitoring from the dorsal distal phalanges.\",\"authors\":\"Noelle Davis,Pooja Mehta,Amanda Kang,Liam Gillan,Jussi Hiltunen,Ali Javey\",\"doi\":\"10.1039/d5lc00586h\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"We present a fingernail-mounted microfluidic sweat sensor, the sNail, that leverages the anatomical and mechanical advantages of the nail plate and adjacent dorsal finger skin-regions that are uniquely stiff and stable yet underutilized for wearable biosensing. In contrast to fully soft, skin-mounted sensors, our device exploits the rigidity of the nail to host microfluidics that remain stable under typical daily finger motion. The platform incorporates a hydrogel-filled sweat collection well and stretchable thermoplastic polyurethane (TPU) microfluidics, fabricated via scalable laserjet printing and laser cutting. We demonstrate frequent sweat rate monitoring across multiple fingers and subjects during activities ranging from walking to typing, and capture dynamic changes in sweat rate associated with both physical exertion and psychological stress. This nail-mounted approach enables unobtrusive, informative sweat biosensing, paving the way for broader adoption in everyday settings.\",\"PeriodicalId\":85,\"journal\":{\"name\":\"Lab on a Chip\",\"volume\":\"13 1\",\"pages\":\"\"},\"PeriodicalIF\":5.4000,\"publicationDate\":\"2025-09-24\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Lab on a Chip\",\"FirstCategoryId\":\"5\",\"ListUrlMain\":\"https://doi.org/10.1039/d5lc00586h\",\"RegionNum\":2,\"RegionCategory\":\"工程技术\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"BIOCHEMICAL RESEARCH METHODS\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Lab on a Chip","FirstCategoryId":"5","ListUrlMain":"https://doi.org/10.1039/d5lc00586h","RegionNum":2,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"BIOCHEMICAL RESEARCH METHODS","Score":null,"Total":0}
引用次数: 0

摘要

我们提出了一种安装在指甲上的微流体汗液传感器,蜗牛,它利用了指甲板和邻近手指背侧皮肤区域的解剖学和力学优势,这些区域具有独特的硬度和稳定性,但尚未充分利用可穿戴生物传感。与完全柔软的皮肤传感器相比,我们的设备利用指甲的刚性来承载微流体,在典型的日常手指运动下保持稳定。该平台结合了一个水凝胶填充的汗液收集孔和可拉伸的热塑性聚氨酯(TPU)微流体,通过可扩展的激光喷射打印和激光切割制造。我们展示了在从走路到打字的活动中,对多个手指和受试者进行频繁的出汗率监测,并捕获了与体力消耗和心理压力相关的出汗率的动态变化。这种安装在指甲上的方法可以实现不显眼的、信息丰富的汗液生物传感,为在日常环境中更广泛的采用铺平了道路。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
sNails: sweat-sensing nails for unobtrusive, wearable microfluidic sweat monitoring from the dorsal distal phalanges.
We present a fingernail-mounted microfluidic sweat sensor, the sNail, that leverages the anatomical and mechanical advantages of the nail plate and adjacent dorsal finger skin-regions that are uniquely stiff and stable yet underutilized for wearable biosensing. In contrast to fully soft, skin-mounted sensors, our device exploits the rigidity of the nail to host microfluidics that remain stable under typical daily finger motion. The platform incorporates a hydrogel-filled sweat collection well and stretchable thermoplastic polyurethane (TPU) microfluidics, fabricated via scalable laserjet printing and laser cutting. We demonstrate frequent sweat rate monitoring across multiple fingers and subjects during activities ranging from walking to typing, and capture dynamic changes in sweat rate associated with both physical exertion and psychological stress. This nail-mounted approach enables unobtrusive, informative sweat biosensing, paving the way for broader adoption in everyday settings.
求助全文
通过发布文献求助,成功后即可免费获取论文全文。 去求助
来源期刊
Lab on a Chip
Lab on a Chip 工程技术-化学综合
CiteScore
11.10
自引率
8.20%
发文量
434
审稿时长
2.6 months
期刊介绍: Lab on a Chip is the premiere journal that publishes cutting-edge research in the field of miniaturization. By their very nature, microfluidic/nanofluidic/miniaturized systems are at the intersection of disciplines, spanning fundamental research to high-end application, which is reflected by the broad readership of the journal. Lab on a Chip publishes two types of papers on original research: full-length research papers and communications. Papers should demonstrate innovations, which can come from technical advancements or applications addressing pressing needs in globally important areas. The journal also publishes Comments, Reviews, and Perspectives.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:604180095
Book学术官方微信