研究交流：TIPS术后累积自发性门静脉分流面积减少及其对预后的影响。

IF 6.7 1区医学 Q1 GASTROENTEROLOGY & HEPATOLOGY

Alimentary Pharmacology & Therapeutics Pub Date : 2025-09-24 DOI:10.1111/apt.70381

Marlene Hintersteininger,Theresa Müllner-Bucsics,Susanna Riegler,Nina Dominik,Georg Kramer,Christian Sebesta,Paul Thöne,Ulrika Asenbaum,Lukas Reider,Maria Schoder,Michael Trauner,Mattias Mandorfer,Thomas Reiberger,Lukas Hartl,Katharina Lampichler

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引用次数: 0

摘要

我们评估了经颈静脉肝内门静脉分流术（TIPS）后自发性门静脉分流术（SPSS）的动力学。纳入了90例覆盖TIPS放置和TIPS前后对比增强CT扫描的患者。统计SPSS总面积和分流总面积（包括TIPS）。TIPS后SPSS面积中位数（67.2-15.7 mm2, p < 0.001）减小，而总分流面积保持不变（67.2-75.8 mm2, p = 0.170）。相对SPSS面积减少是死亡率的独立保护因素（asHR: 0.19; 95% CI: 0.04-0.88; p = 0.034）。综上所述，TIPS后SPSS下降和SPSS相对面积变化与生存独立相关，而总分流面积保持不变。

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Research Communication: The Cumulated Spontaneous Portosystemic Shunts (SPSS) Area Decreases After TIPS and Impacts on Prognosis.

We evaluated the dynamics of spontaneous portosystemic shunts (SPSS) after transjugular intrahepatic portosystemic shunt (TIPS). Ninety patients with covered TIPS placement and contrast-enhanced CT scans before and after TIPS were included. Total SPSS area and total shunt area (including TIPS) were assessed. Median SPSS area (67.2-15.7 mm2; p < 0.001) decreased after TIPS, while total shunt area remained unchanged (67.2-75.8 mm2; p = 0.170). Relative SPSS area decrease was an independent protective factor for mortality (asHR: 0.19; 95% CI: 0.04-0.88; p = 0.034). In conclusion, SPSS decrease after TIPS and relative SPSS area change is independently linked to survival, while total shunt area remains unaltered.

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来源期刊

Alimentary Pharmacology & Therapeutics 医学-胃肠肝病学

CiteScore

15.60

自引率

7.90%

发文量

527

审稿时长

3-6 weeks

期刊介绍： Alimentary Pharmacology & Therapeutics is a global pharmacology journal focused on the impact of drugs on the human gastrointestinal and hepato-biliary systems. It covers a diverse range of topics, often with immediate clinical relevance to its readership.