美国放射治疗对气候和健康的影响:估计温室气体排放、DALYs和低分割的潜力。

IF 5.3 1区 医学 Q1 ONCOLOGY
Katie E Lichter, Alyssa Asaro, Muhammad Mustafa Qureshi, Minh Tam Truong, Akash Parekh, Alon Witztum, Chirjiv Anand, Genevieve S Silva, Trevor Royce, Nicholas G Zaorsky, Surbhi Grover, May Abdel-Wahab, Cassandra Thiel, Matthew J Eckelman, Nicolas Prionas, Sue S Yom, Osama Mohamad
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引用次数: 0

摘要

背景/目的:气候变化是一场全球性危机,美国8.5-10%的温室气体(GHG)排放来自医疗保健行业。已知放射肿瘤学,特别是通过患者转移进行外束放射治疗(EBRT),会导致这些排放。在本研究中,我们的目标是量化美国EBRT二氧化碳当量(CO2e)的年度温室气体排放量,根据残疾调整生命年(DALYs)损失估计其对人类健康的下游影响,并评估通过增加采用低分割来减少排放的潜力,以早期乳腺癌为模型。材料/方法:这是一项使用生命周期评估(LCA)方法的回顾性分析,整合了患者运输和能源使用的真实数据,并模拟了先前建立的乳房治疗指南的替代分娩期安排。该研究包括556,426名接受EBRT治疗的9种癌症类型(乳腺癌、中枢神经系统、胃肠道、泌尿生殖系统、妇科、头颈部、肌肉骨骼、皮肤和胸部)的患者,这些患者记录在2019年和2020年的国家癌症数据库(NCDB)中。其中,49,909例早期乳腺癌(I-II期,淋巴结阴性)患者进行了低分割情景建模。结果:2019年和2020年,美国的EBRT处理分别产生了330万吨和270万吨二氧化碳当量。相应的DALYs损失为2019年的1040年和2020年的863年。模拟表明,在符合条件的乳腺癌治疗中增加使用低分割可以减少高达64%的温室气体排放。结论:建立EBRT的美国温室气体排放基线为确定减少排放的机会提供了基础。从环境角度调查临床实践可以产生双重好处:提高护理质量和显著减少排放。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
The climate and health impact of U.S. radiation therapy: estimating greenhouse gas emissions, DALYs, and potential of hypofractionation.

Background/purpose: Climate change is a global crisis, with the healthcare sector contributing 8.5-10% of greenhouse gas (GHG) emissions in the United States (U.S.). Radiation oncology, particularly through patient transportation for external beam radiation therapy (EBRT), is known to contribute to these emissions. In this study, we aim to quantify the annual GHG emissions in carbon dioxide equivalents (CO2e) from EBRT in the U.S., estimate their down-stream impact on human health in terms of disability-adjusted life-years (DALYs) lost, and evaluate the potential reduction in emissions through increased adoption of hypofractionation, using early-stage breast cancer as a model.

Materials/methods: This is a retrospective analysis using life cycle assessment (LCA) methodologies, integrating real-world data on patient transportation and energy use, and simulations of alternative fractionation schedules following previously established breast treatment guidelines. The study included 556,426 patients who received EBRT for nine cancer types (breast, central nervous system, gastrointestinal, genitourinary, gynecological, head and neck, musculoskeletal, skin, and thoracic), as recorded in the National Cancer Database (NCDB) in 2019 and 2020. Of these, 49,909 patients with early-stage breast cancer (stages I-II, node-negative) were modeled for hypofractionation scenarios.

Results: In 2019 and 2020, EBRT treatments in the U.S. resulted in 3.3 and 2.7 million metric tonnes of CO2e, respectively. Corresponding DALYs lost were 1,040 in 2019 and 863 in 2020. Simulations showed that increasing use of hypofractionation for eligible breast cancer treatments could reduce GHG emissions by up to 64%.

Conclusions: Establishing baseline U.S. GHG emissions from EBRT offers a foundation for identifying opportunities to mitigate emissions. Investigating clinical practices from an environmental perspective can yield dual benefits: improved quality of care and significant emissions reductions.

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来源期刊
Radiotherapy and Oncology
Radiotherapy and Oncology 医学-核医学
CiteScore
10.30
自引率
10.50%
发文量
2445
审稿时长
45 days
期刊介绍: Radiotherapy and Oncology publishes papers describing original research as well as review articles. It covers areas of interest relating to radiation oncology. This includes: clinical radiotherapy, combined modality treatment, translational studies, epidemiological outcomes, imaging, dosimetry, and radiation therapy planning, experimental work in radiobiology, chemobiology, hyperthermia and tumour biology, as well as data science in radiation oncology and physics aspects relevant to oncology.Papers on more general aspects of interest to the radiation oncologist including chemotherapy, surgery and immunology are also published.
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