基于深度学习和电子健康记录数据的黏着性小肠梗阻绞窄风险多模态预测模型。

IF 1.5 4区 医学 Q4 MEDICINE, RESEARCH & EXPERIMENTAL
Journal of International Medical Research Pub Date : 2025-09-01 Epub Date: 2025-09-22 DOI:10.1177/03000605251378951
Han Wang, Jing Wu, Xianglin Ding, Zhaocheng Ruan, Shiqi Zhu, Yu Wang, Lihe Liu, Jiaxi Lin, Jinzhou Zhu, Xin Chen
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引用次数: 0

摘要

本研究旨在通过整合基于深度学习的计算机断层成像特征和临床电子健康记录,开发并验证粘连性小肠梗阻患者绞窄风险的多模式预测模型。方法在三家医院进行了一项回顾性、观察性、多中心研究,225例患者的数据用于模型开发,123例患者用于外部验证。三维卷积神经网络与ResNet50骨干被用来分割腹部区域从计算机断层扫描和分类绞杀的风险。多模态模型使用XGBoost算法将深度学习预测与顶级电子健康记录功能集成在一起;通过变量重要性排序和局部可解释模型不可知的解释来实现全局和局部可解释性。结果多模态模型在预测入院7天内绞杀方面表现优异,训练集曲线下面积为0.915,测试集曲线下面积为0.912,优于单模态模型。校准图显示预测结果和观察结果之间有良好的一致性,决策曲线分析显示出显著的临床实用性,净重分类改进证实了深度学习增强了模型的预测能力。结论本研究强调了多模式人工智能结合临床数据在提高粘连性小肠梗阻诊断准确性和支持临床决策方面的潜力。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

Multimodal predictive model for strangulation risk in adhesive small bowel obstruction using deep learning and electronic health record data.

Multimodal predictive model for strangulation risk in adhesive small bowel obstruction using deep learning and electronic health record data.

Multimodal predictive model for strangulation risk in adhesive small bowel obstruction using deep learning and electronic health record data.

Multimodal predictive model for strangulation risk in adhesive small bowel obstruction using deep learning and electronic health record data.

AimsThis study aimed to develop and validate a multimodal predictive model for the risk of strangulation in adhesive small bowel obstruction by integrating deep learning-based computed tomography imaging features and clinical electronic health records.MethodsA retrospective, observational, multicenter study was conducted across three hospitals, with data from 225 patients used for model development and 123 patients for external validation. A three-dimensional convolutional neural network with a ResNet50 backbone was used to segment abdominal regions from computed tomography scans and classify strangulation risk. The multimodal model integrated deep learning predictions with top electronic health record features using the XGBoost algorithm; global and local interpretability were achieved through variable importance ranking and local interpretable model-agnostic explanations.ResultsThe multimodal model demonstrated superior performance in predicting strangulation within 7 days of admission, achieving an area under the curve of 0.915 in the training set and 0.912 in the test set, outperforming single-modality models. Calibration plots showed good alignment between predicted and observed outcomes, decision curve analysis demonstrated significant clinical utility, and net reclassification improvement confirmed that deep learning enhanced the model's predictive ability.ConclusionThis study highlights the potential of multimodal artificial intelligence combined with clinical data to improve diagnostic accuracy and support clinical decision making in adhesive small bowel obstruction.

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来源期刊
CiteScore
3.20
自引率
0.00%
发文量
555
审稿时长
1 months
期刊介绍: _Journal of International Medical Research_ is a leading international journal for rapid publication of original medical, pre-clinical and clinical research, reviews, preliminary and pilot studies on a page charge basis. As a service to authors, every article accepted by peer review will be given a full technical edit to make papers as accessible and readable to the international medical community as rapidly as possible. Once the technical edit queries have been answered to the satisfaction of the journal, the paper will be published and made available freely to everyone under a creative commons licence. Symposium proceedings, summaries of presentations or collections of medical, pre-clinical or clinical data on a specific topic are welcome for publication as supplements. Print ISSN: 0300-0605
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