{"title":"帕金森病，第二版。","authors":"Serge Przedborski, Stanley Fahn","doi":"10.1101/cshperspect.a041954","DOIUrl":null,"url":null,"abstract":"<p><p>Parkinson's disease (PD), once stigmatized and hidden, is now widely acknowledged by patients and recognized by the public. Yet, fundamental questions about the disease's origins, mechanisms, and progression remain unanswered. The second edition of <i>Parkinson's Disease</i> provides an integrated, accessible resource for clinicians and research scientists. It offers a comprehensive bench-to-bedside overview of PD, with contributions from leading experts in the clinical spectrum and the pathology, genetics, and neurobiological aspects of the condition. New chapters reflect recent advances in areas such as disease progression, biomarkers, cell-based therapies, lipid biology, and the gut-brain axis. The book emphasizes the need for interdisciplinary collaboration and serves as an educational entry point to the field and a strategic guide to future PD research.</p>","PeriodicalId":10452,"journal":{"name":"Cold Spring Harbor perspectives in medicine","volume":" ","pages":""},"PeriodicalIF":10.1000,"publicationDate":"2025-09-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Parkinson's Disease, Second Edition.\",\"authors\":\"Serge Przedborski, Stanley Fahn\",\"doi\":\"10.1101/cshperspect.a041954\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>Parkinson's disease (PD), once stigmatized and hidden, is now widely acknowledged by patients and recognized by the public. Yet, fundamental questions about the disease's origins, mechanisms, and progression remain unanswered. The second edition of <i>Parkinson's Disease</i> provides an integrated, accessible resource for clinicians and research scientists. It offers a comprehensive bench-to-bedside overview of PD, with contributions from leading experts in the clinical spectrum and the pathology, genetics, and neurobiological aspects of the condition. New chapters reflect recent advances in areas such as disease progression, biomarkers, cell-based therapies, lipid biology, and the gut-brain axis. The book emphasizes the need for interdisciplinary collaboration and serves as an educational entry point to the field and a strategic guide to future PD research.</p>\",\"PeriodicalId\":10452,\"journal\":{\"name\":\"Cold Spring Harbor perspectives in medicine\",\"volume\":\" \",\"pages\":\"\"},\"PeriodicalIF\":10.1000,\"publicationDate\":\"2025-09-22\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Cold Spring Harbor perspectives in medicine\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.1101/cshperspect.a041954\",\"RegionNum\":2,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"MEDICINE, RESEARCH & EXPERIMENTAL\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Cold Spring Harbor perspectives in medicine","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1101/cshperspect.a041954","RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"MEDICINE, RESEARCH & EXPERIMENTAL","Score":null,"Total":0}
Parkinson's disease (PD), once stigmatized and hidden, is now widely acknowledged by patients and recognized by the public. Yet, fundamental questions about the disease's origins, mechanisms, and progression remain unanswered. The second edition of Parkinson's Disease provides an integrated, accessible resource for clinicians and research scientists. It offers a comprehensive bench-to-bedside overview of PD, with contributions from leading experts in the clinical spectrum and the pathology, genetics, and neurobiological aspects of the condition. New chapters reflect recent advances in areas such as disease progression, biomarkers, cell-based therapies, lipid biology, and the gut-brain axis. The book emphasizes the need for interdisciplinary collaboration and serves as an educational entry point to the field and a strategic guide to future PD research.
期刊介绍：
Cold Spring Harbor Perspectives in Medicine is a monthly online publication comprising reviews on different aspects of a variety of diseases, covering everything from the molecular and cellular bases of disease to translational medicine and new therapeutic strategies.
Cold Spring Harbor Perspectives in Medicine is thus unmatched in its depth of coverage and represents an essential source where readers can find informed surveys and critical discussion of advances in molecular medicine.
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