Mirim Shin, Jacob J. Crouse, Meltem Weger, Sarah McKenna, Naomi R. Wray, Elizabeth M. Scott, Ian B. Hickie, Frédéric Gachon
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Insulin resistance as an early marker in youth with mood disorders
Insulin resistance is emerging as an early metabolic risk marker in youth with mood disorders. In this Comment, we examine the interplay of insulin resistance, inflammation and circadian disruption that worsens both metabolic symptoms and mood symptoms, highlighting the potential for early integrated interventions.