{"title":"CL1作为利用生物神经系统功能的平台技术","authors":"Brett J. Kagan","doi":"10.1038/s44222-025-00340-3","DOIUrl":null,"url":null,"abstract":"The CL1 is a scalable device for interacting with in vitro neural cell cultures via electrical activity in a closed-loop real-time environment coupled with an integrated life-support perfusion circuit. Here we explore the key component that constitutes the CL1 along with the various opportunities this platform technology can address.","PeriodicalId":74248,"journal":{"name":"Nature reviews bioengineering","volume":"3 9","pages":"724-725"},"PeriodicalIF":37.6000,"publicationDate":"2025-07-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"The CL1 as a platform technology to leverage biological neural system functions\",\"authors\":\"Brett J. Kagan\",\"doi\":\"10.1038/s44222-025-00340-3\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"The CL1 is a scalable device for interacting with in vitro neural cell cultures via electrical activity in a closed-loop real-time environment coupled with an integrated life-support perfusion circuit. Here we explore the key component that constitutes the CL1 along with the various opportunities this platform technology can address.\",\"PeriodicalId\":74248,\"journal\":{\"name\":\"Nature reviews bioengineering\",\"volume\":\"3 9\",\"pages\":\"724-725\"},\"PeriodicalIF\":37.6000,\"publicationDate\":\"2025-07-07\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Nature reviews bioengineering\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://www.nature.com/articles/s44222-025-00340-3\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Nature reviews bioengineering","FirstCategoryId":"1085","ListUrlMain":"https://www.nature.com/articles/s44222-025-00340-3","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
The CL1 as a platform technology to leverage biological neural system functions
The CL1 is a scalable device for interacting with in vitro neural cell cultures via electrical activity in a closed-loop real-time environment coupled with an integrated life-support perfusion circuit. Here we explore the key component that constitutes the CL1 along with the various opportunities this platform technology can address.
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