{"title":"mrna -脂质纳米颗粒尚未开发的潜力","authors":"","doi":"10.1038/s44222-025-00362-x","DOIUrl":null,"url":null,"abstract":"mRNA–lipid nanoparticles have transformed vaccines and are beginning to have an effect in cancer therapy, yet remain absent in therapies for acute critical illnesses, such as stroke, infarction or other traumatic injuries. Economic disincentives and historical reputation might be behind this gap.","PeriodicalId":74248,"journal":{"name":"Nature reviews bioengineering","volume":"3 9","pages":"715-715"},"PeriodicalIF":37.6000,"publicationDate":"2025-09-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.nature.comhttps://www.nature.com/articles/s44222-025-00362-x.pdf","citationCount":"0","resultStr":"{\"title\":\"The untapped potential of mRNA–lipid nanoparticles\",\"authors\":\"\",\"doi\":\"10.1038/s44222-025-00362-x\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"mRNA–lipid nanoparticles have transformed vaccines and are beginning to have an effect in cancer therapy, yet remain absent in therapies for acute critical illnesses, such as stroke, infarction or other traumatic injuries. Economic disincentives and historical reputation might be behind this gap.\",\"PeriodicalId\":74248,\"journal\":{\"name\":\"Nature reviews bioengineering\",\"volume\":\"3 9\",\"pages\":\"715-715\"},\"PeriodicalIF\":37.6000,\"publicationDate\":\"2025-09-11\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.nature.comhttps://www.nature.com/articles/s44222-025-00362-x.pdf\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Nature reviews bioengineering\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://www.nature.com/articles/s44222-025-00362-x\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Nature reviews bioengineering","FirstCategoryId":"1085","ListUrlMain":"https://www.nature.com/articles/s44222-025-00362-x","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
The untapped potential of mRNA–lipid nanoparticles
mRNA–lipid nanoparticles have transformed vaccines and are beginning to have an effect in cancer therapy, yet remain absent in therapies for acute critical illnesses, such as stroke, infarction or other traumatic injuries. Economic disincentives and historical reputation might be behind this gap.
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