Rachel VanKeulen-Miller, Vincent Fung, Owen S. Fenton
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Using ‘supporting molecules’ (SUMs) to improve mRNA LNP therapies
Lipid nanoparticles deliver mRNA without considering the amount and type of ‘supporting molecules’ (SUMs) available in the cell to process them. Here we discuss how co-delivering SUMs with mRNA payloads can provide a simple yet effective strategy for amplifying their performance toward the creation of safer and more-effective therapeutics.
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