{"title":"Nanomedicine-lipoprotein交互","authors":"S. Moein Moghimi, Dmitri Simberg","doi":"10.1038/s44222-025-00291-9","DOIUrl":null,"url":null,"abstract":"Nanomedicines interact with lipoproteins in the blood, which might result in alterations in both nanomedicine and lipoprotein structure and function. Such interactions could also be exploited for site-specific delivery through a ‘lipoprotein Trojan Horse’ mechanism and to restore dysfunctional lipoproteins.","PeriodicalId":74248,"journal":{"name":"Nature reviews bioengineering","volume":"3 6","pages":"435-437"},"PeriodicalIF":37.6000,"publicationDate":"2025-02-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Nanomedicine–lipoprotein interactions\",\"authors\":\"S. Moein Moghimi, Dmitri Simberg\",\"doi\":\"10.1038/s44222-025-00291-9\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Nanomedicines interact with lipoproteins in the blood, which might result in alterations in both nanomedicine and lipoprotein structure and function. Such interactions could also be exploited for site-specific delivery through a ‘lipoprotein Trojan Horse’ mechanism and to restore dysfunctional lipoproteins.\",\"PeriodicalId\":74248,\"journal\":{\"name\":\"Nature reviews bioengineering\",\"volume\":\"3 6\",\"pages\":\"435-437\"},\"PeriodicalIF\":37.6000,\"publicationDate\":\"2025-02-26\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Nature reviews bioengineering\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://www.nature.com/articles/s44222-025-00291-9\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Nature reviews bioengineering","FirstCategoryId":"1085","ListUrlMain":"https://www.nature.com/articles/s44222-025-00291-9","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Nanomedicines interact with lipoproteins in the blood, which might result in alterations in both nanomedicine and lipoprotein structure and function. Such interactions could also be exploited for site-specific delivery through a ‘lipoprotein Trojan Horse’ mechanism and to restore dysfunctional lipoproteins.