{"title":"工程细胞卵巢激素治疗","authors":"Maria João Sousa, Christiani A. Amorim","doi":"10.1038/s44222-025-00325-2","DOIUrl":null,"url":null,"abstract":"Biomimetic endocrine implants bridge tissue engineering and reproductive medicine to offer adaptive and long-lasting hormone therapies for the treatment of ovarian premature insufficiency and menopause. Their clinical translation requires aligned regulatory, ethical and manufacturing pathways.","PeriodicalId":74248,"journal":{"name":"Nature reviews bioengineering","volume":"3 8","pages":"620-622"},"PeriodicalIF":37.6000,"publicationDate":"2025-06-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Engineering cell-based ovarian hormone therapy\",\"authors\":\"Maria João Sousa, Christiani A. Amorim\",\"doi\":\"10.1038/s44222-025-00325-2\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Biomimetic endocrine implants bridge tissue engineering and reproductive medicine to offer adaptive and long-lasting hormone therapies for the treatment of ovarian premature insufficiency and menopause. Their clinical translation requires aligned regulatory, ethical and manufacturing pathways.\",\"PeriodicalId\":74248,\"journal\":{\"name\":\"Nature reviews bioengineering\",\"volume\":\"3 8\",\"pages\":\"620-622\"},\"PeriodicalIF\":37.6000,\"publicationDate\":\"2025-06-05\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Nature reviews bioengineering\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://www.nature.com/articles/s44222-025-00325-2\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Nature reviews bioengineering","FirstCategoryId":"1085","ListUrlMain":"https://www.nature.com/articles/s44222-025-00325-2","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Biomimetic endocrine implants bridge tissue engineering and reproductive medicine to offer adaptive and long-lasting hormone therapies for the treatment of ovarian premature insufficiency and menopause. Their clinical translation requires aligned regulatory, ethical and manufacturing pathways.
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