衣索比亚西部奥罗米亚州Horo Guduru Wallaga地区孕妇胎膜早破的决定因素：一项病例对照研究

IF 1.7 Q2 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH

Clinical Epidemiology and Global Health Pub Date : 2025-09-16 DOI:10.1016/j.cegh.2025.102188

Bekan Gudata Gindaba, Damiso Geneti Dinagde, Firaol Manigste Moges

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引用次数: 0

摘要

胎膜早破（PROM），发生在妊娠28周后分娩前，是一个与孕产妇和新生儿预后不良相关的主要产科问题。大多数关于PROM的研究都使用了横断面设计，没有人研究过Horo Guduru Wallaga地区的决定因素。因此，本研究旨在通过病例对照设计在该区公立医院中确定与PROM相关的因素。方法于2024年6月20日至2024年8月20日在医院开展不匹配病例对照研究，共纳入314份样本（80例病例和234例对照）。这些病例包括妊娠28至42周的胎膜早破的孕妇，而对照组是妊娠28至42周未发生胎膜早破的孕妇。病例连续选取，对照采用系统抽样法。数据输入Epi-Data 3.10版本，导出到SPSS 24版本进行分析。使用二元逻辑回归识别候选变量，p值<；0.25用于多变量分析。p值为<；0.05，具有统计学意义。结果314例孕妇中，314例（80例，对照组234例）参加了研究。本研究结果显示，流产史[(AOR = 2.4, 95% CI:(1.21,4.78)]、胎膜早破史[(AOR = 3.56, 95% CI:(1.75,7.22)]、羊水过多[(AOR = 3.53, 95% CI:(1.67,7.43)]和营养不良[(AOR = 3.00, 95% CI:(1.62,5.57)]是胎膜早破的决定因素。结论流产史、胎膜早破、羊水过多、孕期营养不良是胎膜早破的潜在决定因素。因此，有流产、羊水过多、营养不良、胎膜早破史的妇女应引起医护人员的重视，以减少胎膜早破的发生。

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Determinants of premature rupture of membrane among pregnant women in Horo Guduru Wallaga zone, Western Oromia, Ethiopia: A case-control study

Problem considered

Premature rupture of membranes (PROM), occurring after 28 weeks of gestation but before labor, is a major obstetric problem linked to poor maternal and neonatal outcomes. Most studies on PROM have used cross-sectional designs, and none have examined its determinants in the Horo Guduru Wallaga Zone. This study, therefore, aimed to identify factors associated with PROM using a case-control design in public hospitals of the zone.

Methods

A hospital-based unmatched case-control study was conducted from June 20, 2024, to August 20, 2024, involving 314 samples (80 cases and 234 controls). The cases consisted of pregnant women with premature rupture of membranes between 28 and 42 weeks of gestation, while the controls were pregnant women between 28 and 42 weeks of gestation without premature rupture of membranes. Cases were selected consecutively, and controls were chosen using systematic sampling. Data were entered into Epi-Data version 3.10 and exported to SPSS version 24 for analysis. Candidate variables were identified using binary logistic regression with a p-value <0.25 for multivariable analysis. Statistical significance was determined at a p-value <0.05.

Results

Out of 314 pregnant women, 314 (80 cases and 234 controls) participated in the study. The result of this study showed that history of abortion [(AOR = 2.4,95 % CI: (1.21,4.78)] history of premature rupture of the membrane[(AOR = 3.56,95 %CI:(1.75,7.22)], polyhydramnios [(AOR = 3.53,95 %CI:(1.67,7.43)] and under nutrition [(AOR = 3.00, 95 % CI: (1.62,5.57)] were determinants of premature rupture of the membrane.

Conclusions

From this study, the history of abortion, premature ruptures of membrane, polyhydramnios, and undernutrition during pregnancy were potential determinants of premature rupture of membrane. Therefore, women with a history of abortion, polyhydramnios, under-nutrition, and pre-mature rupture of membrane should be paid attention to by health care providers to mitigate the occurrence of premature rupture of membrane.

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来源期刊

Clinical Epidemiology and Global Health PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH-

CiteScore

4.60

自引率

7.70%

发文量

218

审稿时长

66 days

期刊介绍： Clinical Epidemiology and Global Health (CEGH) is a multidisciplinary journal and it is published four times (March, June, September, December) a year. The mandate of CEGH is to promote articles on clinical epidemiology with focus on developing countries in the context of global health. We also accept articles from other countries. It publishes original research work across all disciplines of medicine and allied sciences, related to clinical epidemiology and global health. The journal publishes Original articles, Review articles, Evidence Summaries, Letters to the Editor. All articles published in CEGH are peer-reviewed and published online for immediate access and citation.