色素靛蓝素微生物可持续生产研究进展

IF 4.2 3区工程技术 Q2 CHEMISTRY, APPLIED

Dyes and Pigments Pub Date : 2025-09-20 DOI:10.1016/j.dyepig.2025.113262

Chen Qi, Wenjing Zhu, Yangyi Qiao, Yongmin Zheng, Wankui Jiang, Yujia Jiang, Fengxue Xin, Feng Guo, Wenming Zhang, Min Jiang

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引用次数: 0

摘要

颜料广泛应用于各个行业，包括食品、化妆品、纺织品、制药和材料。然而，稳定的天然蓝色色素相对较少，关于微生物蓝色色素的报道仍然有限。在这些色素中，由于人们越来越关注与合成染料相关的潜在健康风险和环境影响，靛蓝素越来越受到关注。因此，生物生产的靛蓝素正成为一种有希望的替代品。尽管有这种兴趣，目前很少有全面的综述系统地总结和讨论微生物靛蓝素的生物合成。本文综述了靛蓝苷的生物合成途径和代谢调控机制，重点介绍了通过代谢和发酵工程提高其合成的策略。此外，我们概述了目前的挑战和未来的前景，在微生物生产靛蓝。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

Advances in the microbial sustainable production of pigment indigoidine

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Advances in the microbial sustainable production of pigment indigoidine

Pigments are extensively used across various industries, including food, cosmetics, textiles, pharmaceuticals, and materials. However, stable natural blue pigments are relatively rare, and reports on microbial blue pigments remain limited. Among these pigments, indigoidine is gaining increasing attention due to growing concerns over the potential health risks and environmental impacts associated with synthetic dyes. As a result, biologically produced indigoidine is emerging as a promising alternative. Despite this interest, there is currently few comprehensive reviews that systematically summarizes and discusses microbial indigoidine biosynthesis. This review provides an overview of the biosynthetic pathways and metabolic regulatory mechanisms involved in indigoidine production, with a particular focus on strategies to enhance its synthesis through metabolic and fermentation engineering. Furthermore, we outline the current challenges and future perspectives in the microbial production of indigoidine.

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来源期刊

Dyes and Pigments 工程技术-材料科学：纺织

CiteScore

8.20

自引率

13.30%

发文量

933

审稿时长

33 days

期刊介绍： Dyes and Pigments covers the scientific and technical aspects of the chemistry and physics of dyes, pigments and their intermediates. Emphasis is placed on the properties of the colouring matters themselves rather than on their applications or the system in which they may be applied. Thus the journal accepts research and review papers on the synthesis of dyes, pigments and intermediates, their physical or chemical properties, e.g. spectroscopic, surface, solution or solid state characteristics, the physical aspects of their preparation, e.g. precipitation, nucleation and growth, crystal formation, liquid crystalline characteristics, their photochemical, ecological or biological properties and the relationship between colour and chemical constitution. However, papers are considered which deal with the more fundamental aspects of colourant application and of the interactions of colourants with substrates or media. The journal will interest a wide variety of workers in a range of disciplines whose work involves dyes, pigments and their intermediates, and provides a platform for investigators with common interests but diverse fields of activity such as cosmetics, reprographics, dye and pigment synthesis, medical research, polymers, etc.