评估利多卡因贴片在第三磨牙拔牙后疼痛管理中的疗效:一项前瞻性的裂口研究

Q1 Medicine
P.S. Tripthi, Rakshita Kumar, Padmaraj Hegde
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引用次数: 0

摘要

第三磨牙拔牙后的术后疼痛是一个值得关注的问题,通常使用阿片类药物和非甾体抗炎药进行治疗,并伴有相当大的副作用。利多卡因贴片,以其局部作用和最小的全身作用而闻名,在治疗各种疼痛状况方面显示出希望。本研究旨在评估5%利多卡因贴片减少第三磨牙拔牙术后疼痛的疗效。方法对30例年龄18-40岁需要双侧拔除下颌阻生第三磨牙的患者进行前瞻性、口裂研究。术后一侧拔牙后应用试验用利多卡因贴片,对侧拔牙后给予标准口服镇痛药。采用视觉模拟评分法(VAS)评估拔牙当天、术后第1天(POD)和第2天(POD)的疼痛程度。如果疼痛超过VAS阈值,则提供额外的贴片或镇痛药。结果试验组VAS平均评分(1.96±0.72)明显低于对照组(2.55±0.35,p = 0.004)。随着时间的推移,两组的疼痛都有明显的减轻,但试验组显示POD 2的疼痛缓解更大(p = 0.000),没有报告主要的不良反应,只有13.3%的人经历了不充分的镇痛,需要第二次贴片。结论5%利多卡因贴片是治疗第三磨牙拔牙术后疼痛的有效替代药物。然而,建议进一步研究它们在减少阿片类药物使用方面的潜力及其在其他小型口腔外科手术中的有效性。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Assessment of efficacy of lignocaine patch in pain management post third molar extraction: A prospective, split mouth study

Introduction

Postoperative pain following third molar extractions is a significant concern, often managed using opioids and NSAIDs, associated with considerable side effects. Lignocaine patches, known for their localized action and minimal systemic effects, have shown promise in managing various pain conditions. This study aimed to evaluate the efficacy of 5 % lignocaine patches in reducing postoperative pain following third molar extractions.

Methodology

A prospective, split-mouth study was conducted on 30 patients aged 18–40 years requiring bilateral extraction of impacted mandibular third molars. Post extraction on one side (test lignocaine patches were applied postoperatively, while post extraction of contralateral side, standard oral analgesics were given. Pain levels were assessed using the Visual Analog Scale (VAS) on the day of extraction, postoperative day (POD) 1 and POD 2. Additional patches or analgesics were provided if pain exceeded VAS thresholds.

Results

The test group reported significantly lower mean VAS scores (1.96 ± 0.72) compared to the control group (2.55 ± 0.35, p = 0.004). Significant reduction in pain was observed in both groups over time, but the test group showed greater pain relief by POD 2 (p = 0.000) and no major adverse effects were reported, only 13.3 % experienced inadequate analgesia, requiring the need of a second patch.

Conclusion

These findings suggest that 5 % lignocaine patches offer an effective alternative to oral analgesics for managing postoperative pain after third molar extractions. Further research, however, is recommended to explore their potential in reducing opioid use and their effectiveness in other minor oral surgical procedures.
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来源期刊
CiteScore
4.90
自引率
0.00%
发文量
133
审稿时长
167 days
期刊介绍: Journal of Oral Biology and Craniofacial Research (JOBCR)is the official journal of the Craniofacial Research Foundation (CRF). The journal aims to provide a common platform for both clinical and translational research and to promote interdisciplinary sciences in craniofacial region. JOBCR publishes content that includes diseases, injuries and defects in the head, neck, face, jaws and the hard and soft tissues of the mouth and jaws and face region; diagnosis and medical management of diseases specific to the orofacial tissues and of oral manifestations of systemic diseases; studies on identifying populations at risk of oral disease or in need of specific care, and comparing regional, environmental, social, and access similarities and differences in dental care between populations; diseases of the mouth and related structures like salivary glands, temporomandibular joints, facial muscles and perioral skin; biomedical engineering, tissue engineering and stem cells. The journal publishes reviews, commentaries, peer-reviewed original research articles, short communication, and case reports.
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