封面：新型无酮功能龙香气味剂：clisen化学可持续合成4-（α-雪松-8-基）丁酮-2- 1和有效的甲氧基衍生物。j . Org。化学33/2025)

IF 2.7 3区化学 Q2 CHEMISTRY, ORGANIC

European Journal of Organic Chemistry Pub Date : 2025-09-23 DOI:10.1002/ejoc.70084

Elisa Kuhnt, Marc Mansfeld, Philip Kraft

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引用次数: 0

摘要

封面上有一种新型龙香气味剂“Ambronova”的高效甲氧基取代成分，与嗅觉受体OR7A17对接，被认为是引起龙香气味的原因。为了保持在宇宙背景下，受体表面被渲染为超新星遗迹的发射星云，其与分子特征的良好契合表明了与双功能甲氧基酮的高度互补性，模仿了酮的功能。更多信息可以在P. Kraft及其同事的研究文章中找到（DOI: 10.1002/ejoc.202500548）。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

Front Cover: Novel Ambergris Odorants Devoid of Ketal Functions: Sustainable Synthesis of 4-(α-Cedren-8-yl)Butan-2-Ones and Potent Methoxy Derivatives by Claisen Chemistry (Eur. J. Org. Chem. 33/2025)

查看原文本刊更多论文

The Front Cover features a highly potent methoxy-substituted constituent of the novel ambergris odorant “Ambronova”, docked to the olfactory receptor OR7A17, assumed to be responsible for eliciting ambergris odor sensations. To remain in the cosmic context, the receptor surface was rendered as an emission nebula of a supernova remnant, and its excellent fit with the molecular features demonstrates the high degree of complementarity with the bifunctional methoxy ketone that mimics a ketal function. More information can be found in the Research Article by P. Kraft and co-workers (DOI: 10.1002/ejoc.202500548).

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来源期刊

European Journal of Organic Chemistry 化学-有机化学

CiteScore

5.40

自引率

3.60%

发文量

752

审稿时长

1 months

期刊介绍： The European Journal of Organic Chemistry (2019 ISI Impact Factor 2.889) publishes Full Papers, Communications, and Minireviews from the entire spectrum of synthetic organic, bioorganic and physical-organic chemistry. It is published on behalf of Chemistry Europe, an association of 16 European chemical societies. The following journals have been merged to form two leading journals, the European Journal of Organic Chemistry and the European Journal of Inorganic Chemistry: Liebigs Annalen Bulletin des Sociétés Chimiques Belges Bulletin de la Société Chimique de France Gazzetta Chimica Italiana Recueil des Travaux Chimiques des Pays-Bas Anales de Química Chimika Chronika Revista Portuguesa de Química ACH—Models in Chemistry Polish Journal of Chemistry.