妊娠期糖尿病妇女发展为2型糖尿病的相关因素

IF 4.1 2区 医学 Q1 MEDICINE, GENERAL & INTERNAL
Junxiu Liu, Chen Yang, Bian Liu, Ryung Kim, Athena Philis-Tsimikas, Carmen Isasi, Diana Wolfe, Carol Levy, Jee-Young Moon, Lihua Li
{"title":"妊娠期糖尿病妇女发展为2型糖尿病的相关因素","authors":"Junxiu Liu, Chen Yang, Bian Liu, Ryung Kim, Athena Philis-Tsimikas, Carmen Isasi, Diana Wolfe, Carol Levy, Jee-Young Moon, Lihua Li","doi":"10.1007/s11524-025-01013-7","DOIUrl":null,"url":null,"abstract":"<p><p>While both individual- and neighborhood-level factors play a role in the progression from gestational diabetes mellitus (GDM) to type 2 diabetes mellitus (T2DM), few studies have simultaneously examined these two sets of factors. In this retrospective cohort study of 3567 women with a history of GDM, we used multilevel survival analysis to quantify T2DM risk associated with patient-level and neighborhood-level factors. During a mean follow-up of 2.2 years, 195 women (5.5%) developed T2DM. Statistically significant risk factors of T2DM progression included Black or Asian race, preeclampsia, family history of diabetes, and overweight or obesity. Importantly, residing in neighborhoods with a top tertile social deprivation index was also associated with increased risk (HR = 1.78, 95% CI: 1.01-3.14). In addition, after accounting for other factors, the residual clustering associated with neighborhoods conferred a 19% higher risk. Interventions addressing both individual- and neighborhood-level factors, including socioeconomic disparities, are critical to reducing the risk of T2DM in women with GDM.</p>","PeriodicalId":49964,"journal":{"name":"Journal of Urban Health-Bulletin of the New York Academy of Medicine","volume":" ","pages":"877-882"},"PeriodicalIF":4.1000,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12484436/pdf/","citationCount":"0","resultStr":"{\"title\":\"Factors Associated with Progression to Type 2 Diabetes among Women with Gestational Diabetes.\",\"authors\":\"Junxiu Liu, Chen Yang, Bian Liu, Ryung Kim, Athena Philis-Tsimikas, Carmen Isasi, Diana Wolfe, Carol Levy, Jee-Young Moon, Lihua Li\",\"doi\":\"10.1007/s11524-025-01013-7\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>While both individual- and neighborhood-level factors play a role in the progression from gestational diabetes mellitus (GDM) to type 2 diabetes mellitus (T2DM), few studies have simultaneously examined these two sets of factors. In this retrospective cohort study of 3567 women with a history of GDM, we used multilevel survival analysis to quantify T2DM risk associated with patient-level and neighborhood-level factors. During a mean follow-up of 2.2 years, 195 women (5.5%) developed T2DM. Statistically significant risk factors of T2DM progression included Black or Asian race, preeclampsia, family history of diabetes, and overweight or obesity. Importantly, residing in neighborhoods with a top tertile social deprivation index was also associated with increased risk (HR = 1.78, 95% CI: 1.01-3.14). In addition, after accounting for other factors, the residual clustering associated with neighborhoods conferred a 19% higher risk. Interventions addressing both individual- and neighborhood-level factors, including socioeconomic disparities, are critical to reducing the risk of T2DM in women with GDM.</p>\",\"PeriodicalId\":49964,\"journal\":{\"name\":\"Journal of Urban Health-Bulletin of the New York Academy of Medicine\",\"volume\":\" \",\"pages\":\"877-882\"},\"PeriodicalIF\":4.1000,\"publicationDate\":\"2025-08-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12484436/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of Urban Health-Bulletin of the New York Academy of Medicine\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.1007/s11524-025-01013-7\",\"RegionNum\":2,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2025/9/22 0:00:00\",\"PubModel\":\"Epub\",\"JCR\":\"Q1\",\"JCRName\":\"MEDICINE, GENERAL & INTERNAL\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Urban Health-Bulletin of the New York Academy of Medicine","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1007/s11524-025-01013-7","RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2025/9/22 0:00:00","PubModel":"Epub","JCR":"Q1","JCRName":"MEDICINE, GENERAL & INTERNAL","Score":null,"Total":0}
引用次数: 0

摘要

虽然个体和社区水平的因素在妊娠期糖尿病(GDM)向2型糖尿病(T2DM)的进展中都起作用,但很少有研究同时检查这两组因素。在这项对3567名有GDM病史的女性的回顾性队列研究中,我们使用多水平生存分析来量化与患者水平和社区水平因素相关的T2DM风险。在平均2.2年的随访期间,195名女性(5.5%)发展为2型糖尿病。有统计学意义的T2DM进展危险因素包括黑人或亚洲种族、先兆子痫、糖尿病家族史、超重或肥胖。重要的是,居住在社会剥夺指数最高的社区也与风险增加有关(HR = 1.78, 95% CI: 1.01-3.14)。此外,在考虑了其他因素后,与社区相关的残余聚类使风险增加了19%。针对个人和社区因素的干预措施,包括社会经济差异,对于降低GDM妇女发生2型糖尿病的风险至关重要。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Factors Associated with Progression to Type 2 Diabetes among Women with Gestational Diabetes.

While both individual- and neighborhood-level factors play a role in the progression from gestational diabetes mellitus (GDM) to type 2 diabetes mellitus (T2DM), few studies have simultaneously examined these two sets of factors. In this retrospective cohort study of 3567 women with a history of GDM, we used multilevel survival analysis to quantify T2DM risk associated with patient-level and neighborhood-level factors. During a mean follow-up of 2.2 years, 195 women (5.5%) developed T2DM. Statistically significant risk factors of T2DM progression included Black or Asian race, preeclampsia, family history of diabetes, and overweight or obesity. Importantly, residing in neighborhoods with a top tertile social deprivation index was also associated with increased risk (HR = 1.78, 95% CI: 1.01-3.14). In addition, after accounting for other factors, the residual clustering associated with neighborhoods conferred a 19% higher risk. Interventions addressing both individual- and neighborhood-level factors, including socioeconomic disparities, are critical to reducing the risk of T2DM in women with GDM.

求助全文
通过发布文献求助,成功后即可免费获取论文全文。 去求助
来源期刊
Journal of Urban Health-Bulletin of the New York Academy of Medicine
Journal of Urban Health-Bulletin of the New York Academy of Medicine 医学-公共卫生、环境卫生与职业卫生
CiteScore
9.10
自引率
3.00%
发文量
105
审稿时长
6-12 weeks
期刊介绍: The Journal of Urban Health is the premier and authoritative source of rigorous analyses to advance the health and well-being of people in cities. The Journal provides a platform for interdisciplinary exploration of the evidence base for the broader determinants of health and health inequities needed to strengthen policies, programs, and governance for urban health. The Journal publishes original data, case studies, commentaries, book reviews, executive summaries of selected reports, and proceedings from important global meetings. It welcomes submissions presenting new analytic methods, including systems science approaches to urban problem solving. Finally, the Journal provides a forum linking scholars, practitioners, civil society, and policy makers from the multiple sectors that can influence the health of urban populations.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:604180095
Book学术官方微信