口服胃疗及家庭治疗对幽门螺杆菌根除及复发的影响。

IF 1.1 4区 医学 Q4 GASTROENTEROLOGY & HEPATOLOGY
Zhiqiang Chen, Fang Yuan, Chao Pan
{"title":"口服胃疗及家庭治疗对幽门螺杆菌根除及复发的影响。","authors":"Zhiqiang Chen, Fang Yuan, Chao Pan","doi":"10.1016/j.ajg.2025.08.005","DOIUrl":null,"url":null,"abstract":"<p><strong>Background and study aims: </strong>Helicobacter pylori (H. pylori) infections are notably difficult to eradicate due to high antibiotic resistance and frequent reinfection. This study evaluates the effectiveness of combining oral and gastric treatments with synchronized family therapy compared to standard therapy for H. pylori management.</p><p><strong>Patients and methods: </strong>Conducted at Cangshan Hospital of the 900th Hospital of the Joint Logistics Support Force of the Chinese People's Liberation Army, the study included 180 patients divided into three groups: standard triple therapy (Group A), triple therapy plus oral treatment (Group B), and triple therapy with oral treatment and synchronized family therapy (Group C). Eradication and recurrence were measured at 3 and 6 months using stool antigen tests and 14C-urea breath tests.</p><p><strong>Results: </strong>Initial eradication rates were similar across the three groups. By 3 months, eradication rates reached 76.7 % in Group A, 86.7 % in Group B, and 93.3 % in Group C. At 6 months, these rates were 61.7 %, 66.7 %, and 90 %, respectively. Concurrently, recurrence rates at 6 months climbed to 33.9 % and 29.8 % in Groups A and B, respectively, but remained low at 5.3 % in Group C.</p><p><strong>Conclusion: </strong>The addition of synchronized family therapy significantly enhances long-term eradication and reduces recurrence rates, suggesting its potential for incorporation into standard H. pylori treatment protocols.</p>","PeriodicalId":48674,"journal":{"name":"Arab Journal of Gastroenterology","volume":" ","pages":""},"PeriodicalIF":1.1000,"publicationDate":"2025-09-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Effects of oral-gastric treatment and family therapy on H. Pylori eradication and recurrence.\",\"authors\":\"Zhiqiang Chen, Fang Yuan, Chao Pan\",\"doi\":\"10.1016/j.ajg.2025.08.005\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Background and study aims: </strong>Helicobacter pylori (H. pylori) infections are notably difficult to eradicate due to high antibiotic resistance and frequent reinfection. This study evaluates the effectiveness of combining oral and gastric treatments with synchronized family therapy compared to standard therapy for H. pylori management.</p><p><strong>Patients and methods: </strong>Conducted at Cangshan Hospital of the 900th Hospital of the Joint Logistics Support Force of the Chinese People's Liberation Army, the study included 180 patients divided into three groups: standard triple therapy (Group A), triple therapy plus oral treatment (Group B), and triple therapy with oral treatment and synchronized family therapy (Group C). Eradication and recurrence were measured at 3 and 6 months using stool antigen tests and 14C-urea breath tests.</p><p><strong>Results: </strong>Initial eradication rates were similar across the three groups. By 3 months, eradication rates reached 76.7 % in Group A, 86.7 % in Group B, and 93.3 % in Group C. At 6 months, these rates were 61.7 %, 66.7 %, and 90 %, respectively. Concurrently, recurrence rates at 6 months climbed to 33.9 % and 29.8 % in Groups A and B, respectively, but remained low at 5.3 % in Group C.</p><p><strong>Conclusion: </strong>The addition of synchronized family therapy significantly enhances long-term eradication and reduces recurrence rates, suggesting its potential for incorporation into standard H. pylori treatment protocols.</p>\",\"PeriodicalId\":48674,\"journal\":{\"name\":\"Arab Journal of Gastroenterology\",\"volume\":\" \",\"pages\":\"\"},\"PeriodicalIF\":1.1000,\"publicationDate\":\"2025-09-20\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Arab Journal of Gastroenterology\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.1016/j.ajg.2025.08.005\",\"RegionNum\":4,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q4\",\"JCRName\":\"GASTROENTEROLOGY & HEPATOLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Arab Journal of Gastroenterology","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1016/j.ajg.2025.08.005","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"GASTROENTEROLOGY & HEPATOLOGY","Score":null,"Total":0}
引用次数: 0

摘要

背景与研究目的:幽门螺杆菌(Helicobacter pylori, H. pylori)感染由于其高耐药性和频繁的再感染而难以根治。本研究评估了与标准治疗相比,口服和胃联合治疗与同步家庭治疗对幽门螺杆菌治疗的有效性。患者和方法:研究在中国人民解放军联勤保障部队第900医院苍山医院进行,纳入180例患者,分为三组:标准三联治疗(A组)、三联治疗加口服治疗(B组)、三联治疗加口服治疗和家庭同步治疗(C组)。3个月和6个月时用粪便抗原试验和14c -尿素呼气试验测定根除和复发率。结果:三组的初始根除率相似。3个月时,A组根除率为76.7%,B组为86.7%,c组为93.3%。6个月时,A组根除率为61.7%,B组为66.7%,c组为90%。同时,A组和B组的6个月复发率分别攀升至33.9%和29.8%,但c组的复发率仍然很低,为5.3%。结论:同步家庭治疗的加入显著增强了长期根除,降低了复发率,表明其有可能纳入标准的幽门螺杆菌治疗方案。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Effects of oral-gastric treatment and family therapy on H. Pylori eradication and recurrence.

Background and study aims: Helicobacter pylori (H. pylori) infections are notably difficult to eradicate due to high antibiotic resistance and frequent reinfection. This study evaluates the effectiveness of combining oral and gastric treatments with synchronized family therapy compared to standard therapy for H. pylori management.

Patients and methods: Conducted at Cangshan Hospital of the 900th Hospital of the Joint Logistics Support Force of the Chinese People's Liberation Army, the study included 180 patients divided into three groups: standard triple therapy (Group A), triple therapy plus oral treatment (Group B), and triple therapy with oral treatment and synchronized family therapy (Group C). Eradication and recurrence were measured at 3 and 6 months using stool antigen tests and 14C-urea breath tests.

Results: Initial eradication rates were similar across the three groups. By 3 months, eradication rates reached 76.7 % in Group A, 86.7 % in Group B, and 93.3 % in Group C. At 6 months, these rates were 61.7 %, 66.7 %, and 90 %, respectively. Concurrently, recurrence rates at 6 months climbed to 33.9 % and 29.8 % in Groups A and B, respectively, but remained low at 5.3 % in Group C.

Conclusion: The addition of synchronized family therapy significantly enhances long-term eradication and reduces recurrence rates, suggesting its potential for incorporation into standard H. pylori treatment protocols.

求助全文
通过发布文献求助,成功后即可免费获取论文全文。 去求助
来源期刊
Arab Journal of Gastroenterology
Arab Journal of Gastroenterology Medicine-Gastroenterology
CiteScore
2.70
自引率
0.00%
发文量
52
期刊介绍: Arab Journal of Gastroenterology (AJG) publishes different studies related to the digestive system. It aims to be the foremost scientific peer reviewed journal encompassing diverse studies related to the digestive system and its disorders, and serving the Pan-Arab and wider community working on gastrointestinal disorders.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:604180095
Book学术官方微信