Hui Hu, Hao Chen, Zengpeng Yu, Yudong Zhou, Lusheng Li, Xuan Zhai, Ping Liang, Jun Tang
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Clinical outcome and health-related quality of life in Pediatric intracranial aneurysm, a single-center experience.
Aim: To investigate the association of treatment approaches on the clinical outcomes and health-related quality of life (HRQL) of Pediatric intracranial aneurysms (PIAs) at our institution.
Method: A retrospective analysis of 37 children with PIAs treated from 2015 to 2022. Clinical outcomes were evaluated using the modified Rankin Score (mRS) and Lovett scale. Additionally, the HRQL was assessed using the PedsQL 4.0 questionnaire.
Results: Thirty-seven children were admitted with 41 aneurysms. Of these, 15 patients underwent surgical treatment, 16 received endovascular therapy, and 6 were managed conservatively. After an average follow-up period of 2.8 years, the median mRS was 0 for endovascular therapy against 1.5 for surgical treatment (p=0.443). Similarly, limb muscle strength was higher in the endovascular group (5 vs. 4, p=0.433). PedsQL 4.0 assessments demonstrated excellent reliability (α=0.907), with no significant difference between the endovascular and surgical groups in overall HRQL (p=0.390, 95% CI: -6.892 to 16.978). However, the endovascular group showed a trend toward improved quality of life, including physical, emotional, and social functioning.
Interprtation: Active treatments yield favorable outcomes for children with PIAs. Our study is the first to demonstrate that endovascular approach may offer a beneficial long-term improvement in HRQL for children with PIAs.
期刊介绍：
World Neurosurgery has an open access mirror journal World Neurosurgery: X, sharing the same aims and scope, editorial team, submission system and rigorous peer review.
The journal''s mission is to:
-To provide a first-class international forum and a 2-way conduit for dialogue that is relevant to neurosurgeons and providers who care for neurosurgery patients. The categories of the exchanged information include clinical and basic science, as well as global information that provide social, political, educational, economic, cultural or societal insights and knowledge that are of significance and relevance to worldwide neurosurgery patient care.
-To act as a primary intellectual catalyst for the stimulation of creativity, the creation of new knowledge, and the enhancement of quality neurosurgical care worldwide.
-To provide a forum for communication that enriches the lives of all neurosurgeons and their colleagues; and, in so doing, enriches the lives of their patients.
Topics to be addressed in World Neurosurgery include: EDUCATION, ECONOMICS, RESEARCH, POLITICS, HISTORY, CULTURE, CLINICAL SCIENCE, LABORATORY SCIENCE, TECHNOLOGY, OPERATIVE TECHNIQUES, CLINICAL IMAGES, VIDEOS
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