大麻诱导的年轻人心脏骤停:一例报告。

IF 0.7 Q3 MEDICINE, GENERAL & INTERNAL
Sana Irshad, Parth Adrejiya, Mohammad Abubaker, Theophilus Adatsi, Oluchi Idenyi, Srikanth Maddika, Swathi Gorle, Abhishek Thandra, Srinivasa R Chennareddy
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引用次数: 0

摘要

背景四氢大麻酚(THC)是大麻中的精神活性化合物,越来越多地用于娱乐,特别是在年轻人中。虽然通常被认为是无害的,但新出现的证据表明THC与严重的心血管并发症有关,包括QTc延长、室性心律失常和心脏骤停,即使在没有潜在心脏病的个体中也是如此。病例报告一名26岁的女性,有慢性大麻使用史,在心脏骤停后被带到急诊科。她最初的心律是心室颤动,在高级心脏生命支持后恢复了自发循环。初步心电图显示窦性心动过速,QTc间隔为483 ms,尿药物筛查THC阳性。4周后行心导管检查显示冠状动脉正常。她的左心室射血分数最初降低了25-30%,到置管时已恢复正常。她持续缺氧缺血性脑损伤,需要长时间的康复。结论:本病例强调了大麻使用可能诱发危及生命的心律失常,包括QTc延长和心室颤动,即使在没有心血管危险因素的年轻人中也是如此。临床医生应该在类似的情况下对大麻引起的心脏毒性保持高度的怀疑,特别是当大麻的使用变得更加广泛。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Cannabis-Induced Cardiac Arrest in a Young Adult: A Case Report.

BACKGROUND Tetrahydrocannabinol (THC), the psychoactive compound in cannabis, is increasingly used recreationally, especially among young adults. Although often perceived as harmless, emerging evidence links THC to serious cardiovascular complications, including QTc prolongation, ventricular arrhythmias, and sudden cardiac arrest, even in individuals without underlying heart disease. CASE REPORT A 26-year-old woman with a history of chronic cannabis use was brought to the Emergency Department (ED) after having a sudden cardiac arrest. Her initial rhythm was ventricular fibrillation, and return of spontaneous circulation was achieved following advanced cardiac life support. An initial electrocardiogram revealed sinus tachycardia with a QTc interval of 483 ms, and a urine drug screen was positive for THC. Cardiac catheterization performed 4 weeks later revealed normal coronary arteries. Her left ventricular ejection fraction, initially reduced at 25-30%, had normalized by the time of catheterization. She sustained hypoxic-ischemic brain injury, requiring prolonged rehabilitation. CONCLUSIONS This case highlights the potential for cannabis use to induce life-threatening cardiac arrhythmias, including QTc prolongation, and ventricular fibrillation, even in young adults with no prior cardiovascular risk factors. Clinicians should maintain a high index of suspicion for cannabis-induced cardiotoxicity in similar presentations, particularly as cannabis use becomes more widespread.

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来源期刊
American Journal of Case Reports
American Journal of Case Reports Medicine-Medicine (all)
CiteScore
1.80
自引率
0.00%
发文量
599
期刊介绍: American Journal of Case Reports is an international, peer-reviewed scientific journal that publishes single and series case reports in all medical fields. American Journal of Case Reports is issued on a continuous basis as a primary electronic journal. Print copies of a single article or a set of articles can be ordered on demand.
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