免疫治疗时代胃癌淋巴结清扫的再思考

Q3 Medicine
J Chen, Y J Wu, F L Liu
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引用次数: 0

摘要

免疫疗法的快速发展改变了胃癌手术的治疗模式,不断从胃癌晚期治疗的战场向新辅助治疗推进。免疫联合化疗已成为局部进展期胃癌治疗的新趋势。这一变化促使我们重新审视传统胃癌根治术的概念,特别是对淋巴结清扫提出了新的挑战。淋巴结清扫策略作为免疫应答的核心部位,已成为影响胃癌整体疗效的关键因素之一,在免疫治疗浪潮中迫切需要重新优化和评价。从而建立一种更加精准、个性化的胃癌根治性手术新模式,最终实现短期、长期疗效和生活质量的多重改善。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
[Rethinking lymph node dissection in gastric cancer during the era of immunotherapy].

The rapid development of immunotherapy has changed the treatment pattern of gastric cancer surgery, constantly advancing from the battlefield of advanced gastric cancer treatment to neoadjuvant therapy. The combination of immunotherapy and chemotherapy has become a new trend in the treatment of locally advanced gastric cancer. This change has prompted us to re-examine the concept of traditional radical surgery for gastric cancer, especially for lymph node dissection, it presents new challenges. As the core site of immune response, lymph node dissection strategy has become one of the key factors affecting the overall efficacy of gastric cancer, and it urgently needs to be re optimized and evaluated in the wave of immunotherapy. Thus, a more precise and personalized new paradigm for radical gastric cancer surgery can be established, ultimately achieving multiple improvements in short-term and long-term efficacy, as well as quality of life.

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来源期刊
中华胃肠外科杂志
中华胃肠外科杂志 Medicine-Medicine (all)
CiteScore
1.00
自引率
0.00%
发文量
6776
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