{"title":"Doxy-PEP的公共卫生伦理分析：支持和反对的理由-“是”的情况。","authors":"Sam Templeman, Bridget Haire","doi":"10.1071/SH24013","DOIUrl":null,"url":null,"abstract":"<p><p>In September 2023, the Australasian Society for HIV, Viral Hepatitis and Sexual Health Medicine recommended consideration of doxycycline post-exposure prophylaxis to prevent STIs in gay, bisexual and other men who have sex with men. On 6 June 2024, the US Centers for Disease Control and Prevention added the intervention to its clinical guidelines. However, expanding antibiotic use carries the risk of propagating antimicrobial resistance among target STIs and non-target pathogens, prompting some experts to advocate withholding doxycycline post-exposure prophylaxis until further research is done. Thus, the use of doxycycline post-exposure prophylaxis is a question of whether the risk of antimicrobial resistance to the population is justified by the health benefits to gay, bisexual and other men who have sex with men. Here, we outline the public health ethics cases for and against this strategy.</p>","PeriodicalId":22165,"journal":{"name":"Sexual health","volume":"22 ","pages":""},"PeriodicalIF":2.2000,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"A public health ethics analysis of Doxy-PEP: arguments for and against - the 'yes' case.\",\"authors\":\"Sam Templeman, Bridget Haire\",\"doi\":\"10.1071/SH24013\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>In September 2023, the Australasian Society for HIV, Viral Hepatitis and Sexual Health Medicine recommended consideration of doxycycline post-exposure prophylaxis to prevent STIs in gay, bisexual and other men who have sex with men. On 6 June 2024, the US Centers for Disease Control and Prevention added the intervention to its clinical guidelines. However, expanding antibiotic use carries the risk of propagating antimicrobial resistance among target STIs and non-target pathogens, prompting some experts to advocate withholding doxycycline post-exposure prophylaxis until further research is done. Thus, the use of doxycycline post-exposure prophylaxis is a question of whether the risk of antimicrobial resistance to the population is justified by the health benefits to gay, bisexual and other men who have sex with men. Here, we outline the public health ethics cases for and against this strategy.</p>\",\"PeriodicalId\":22165,\"journal\":{\"name\":\"Sexual health\",\"volume\":\"22 \",\"pages\":\"\"},\"PeriodicalIF\":2.2000,\"publicationDate\":\"2025-07-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Sexual health\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.1071/SH24013\",\"RegionNum\":4,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q3\",\"JCRName\":\"INFECTIOUS DISEASES\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Sexual health","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1071/SH24013","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"INFECTIOUS DISEASES","Score":null,"Total":0}
A public health ethics analysis of Doxy-PEP: arguments for and against - the 'yes' case.
In September 2023, the Australasian Society for HIV, Viral Hepatitis and Sexual Health Medicine recommended consideration of doxycycline post-exposure prophylaxis to prevent STIs in gay, bisexual and other men who have sex with men. On 6 June 2024, the US Centers for Disease Control and Prevention added the intervention to its clinical guidelines. However, expanding antibiotic use carries the risk of propagating antimicrobial resistance among target STIs and non-target pathogens, prompting some experts to advocate withholding doxycycline post-exposure prophylaxis until further research is done. Thus, the use of doxycycline post-exposure prophylaxis is a question of whether the risk of antimicrobial resistance to the population is justified by the health benefits to gay, bisexual and other men who have sex with men. Here, we outline the public health ethics cases for and against this strategy.
期刊介绍：
Sexual Health publishes original and significant contributions to the fields of sexual health including HIV/AIDS, Sexually transmissible infections, issues of sexuality and relevant areas of reproductive health. This journal is directed towards those working in sexual health as clinicians, public health practitioners, researchers in behavioural, clinical, laboratory, public health or social, sciences. The journal publishes peer reviewed original research, editorials, review articles, topical debates, case reports and critical correspondence.
Officially sponsored by:
The Australasian Chapter of Sexual Health Medicine of RACP
Sexual Health Society of Queensland
Sexual Health is the official journal of the International Union against Sexually Transmitted Infections (IUSTI), Asia-Pacific, and the Asia-Oceania Federation of Sexology.
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