麻风性麻风异常顺序I型和II型反应：1例报告。

IF 1.5 4区医学 Q3 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH

Transactions of The Royal Society of Tropical Medicine and Hygiene Pub Date : 2025-09-22 DOI:10.1093/trstmh/traf097

Xinyu Qi, Shuqiong Huang

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引用次数: 0

摘要

麻风病在中国是一种罕见且容易误诊的传染病。麻风病反应（LRs）是治疗麻风病的最大挑战。如果不能及早发现并及时治疗LRs，患者就有发展为残疾的风险。I型反应常发生在边缘性麻风中，而II型反应在麻风性麻风中更为普遍。临床上，1型和2型混合LRs的麻风性麻风较少见。本报告详细介绍了一例伴有混合性LRs的麻风性麻风，患者先后出现II型和I型反应。通过1年的多药治疗以及我们在治疗过程中对LRs的及时识别和干预，患者成功治愈，无任何后遗症。

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Unusual sequential type I and II reactions in lepromatous leprosy: a case report.

Leprosy is a rare and easily misdiagnosed infectious disease in China. Leprosy reactions (LRs) are the greatest challenge in the treatment of leprosy. If LRs cannot be identified early and treated in a timely manner, patients are at risk of developing disabilities. Type I reactions often occur in borderline leprosy, whereas type II reactions are more prevalent in lepromatous leprosy. Clinically, lepromatous leprosy with type I and II mixed LRs is less common. This report details a case of lepromatous leprosy with mixed LRs, where the patient sequentially developed type II and then type I reactions. Through 1 y of multidrug therapy and our timely identification and intervention for LRs during treatment, the patient achieved a successful cure without any sequelae.

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来源期刊

Transactions of The Royal Society of Tropical Medicine and Hygiene 医学-公共卫生、环境卫生与职业卫生

CiteScore

4.00

自引率

9.10%

发文量

115

审稿时长

4-8 weeks

期刊介绍： Transactions of the Royal Society of Tropical Medicine and Hygiene publishes authoritative and impactful original, peer-reviewed articles and reviews on all aspects of tropical medicine.