Doxy-PEP的公共卫生伦理分析：支持和反对的理由——“不”的情况。

IF 2.2 4区医学 Q3 INFECTIOUS DISEASES

Sexual health Pub Date : 2025-07-01 DOI:10.1071/SH24008

Shreyas Iyer, Bridget Haire

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引用次数: 0

摘要

2023年9月，澳大利亚艾滋病毒、病毒性肝炎和性健康医学协会建议在男同性恋、双性恋和其他男男性行为者中使用强力霉素预防接触前性传播感染。然而，扩大抗生素的使用会带来在目标性传播感染和非目标病原体之间传播抗菌素耐药性的风险，这促使一些专家主张在进一步研究完成之前不使用强力霉素接触前预防。因此，多西环素暴露前预防的使用是一个问题，即从对同性恋、双性恋和其他男男性行为者的健康益处来看，人群抗菌素耐药性风险是否合理。在这里，我们概述了支持和反对这一战略的公共卫生伦理案例。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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A public health ethics analysis of Doxy-PEP: arguments for and against - the 'no' case.

In September 2023, the Australasian Society for HIV, Viral Hepatitis and Sexual Health Medicine recommended doxycycline pre-exposure prophylaxis to prevent STIs in gay, bisexual and other men who have sex with men. However, expanding antibiotic use carries the risk of propagating antimicrobial resistance among target STIs and non-target pathogens, prompting some experts to advocate withholding doxycycline pre-exposure prophylaxis until further research is done. Thus, the use of doxycycline pre-exposure prophylaxis is a question of whether the risk of antimicrobial resistance to the population is justified by the health benefits to gay, bisexual and other men who have sex with men. Here, we outline the public health ethics cases for and against this strategy.

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来源期刊

Sexual health 医学-传染病学

CiteScore

2.30

自引率

12.50%

发文量

121

审稿时长

6-12 weeks

期刊介绍： Sexual Health publishes original and significant contributions to the fields of sexual health including HIV/AIDS, Sexually transmissible infections, issues of sexuality and relevant areas of reproductive health. This journal is directed towards those working in sexual health as clinicians, public health practitioners, researchers in behavioural, clinical, laboratory, public health or social, sciences. The journal publishes peer reviewed original research, editorials, review articles, topical debates, case reports and critical correspondence. Officially sponsored by: The Australasian Chapter of Sexual Health Medicine of RACP Sexual Health Society of Queensland Sexual Health is the official journal of the International Union against Sexually Transmitted Infections (IUSTI), Asia-Pacific, and the Asia-Oceania Federation of Sexology.