延长静脉运输-静脉流出与资金流出:成本分析。

IF 2.6 3区 医学 Q2 CLINICAL NEUROLOGY
Manisha Koneru, Janet Mei, Hamza Salim, Dhairya Lakhani, Adam Dmytriw, Adrien Guenego, Dylan Wolman, Shyam Majmundar, Achala Vagal, Aakanksha Sriwastwa, Yasmin Aziz, Meisam Hoseinyazdi, Caline Azzi, Risheng Xu, Hanzhang Lu, Elisabeth Marsh, Richard Leigh, Mona Bahouth, Rafael Llinas, Kambiz Nael, Argye Hillis, Gregory Albers, Jeremy Heit, Tobias Faizy, Vivek Yedavalli
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引用次数: 0

摘要

目的:大血管闭塞急性缺血性卒中(AIS-LVO)患者的医疗费用差异很大,尽管获得了成功的再灌注。延长静脉输送(PVT+)是预处理灌注显像中静脉流出不良的新标志,与各种患者预后相关。我们的目的是探讨PVT +与AIS-LVO的急性护理成本估算之间的关系。方法:回顾性分析美国三个中心的成年AIS-LVO患者通过取栓成功再灌注的情况。成本估算来自医疗保险和医疗补助服务中心的全国平均服务数据(2025年)。主要结局是急性干预、影像学和治疗后住院护理直至出院的总成本估计。比较PVT +组和PVT-组的估计值。结果:109例纳入的患者中位年龄为71岁(IQR 62-80)。PVT +患者的急性卒中总护理费用估计显著高于PVT-患者(中位数为36601美元[IQR $24814- 72944美元],p = 0.03)(中位数为24814美元[IQR $16956- 48388美元])。PVT +组治疗后护理费用显著高于PVT-组(p = 0.03)。结论:PVT +显示了作为一种有用的、通用的预处理生物标志物的潜力,结合其他临床数据,预测与急性卒中护理相关的住院资源和成本。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Prolonged venous transit - where venous outflow meets financial outflow: a cost analysis.

Purpose: Healthcare costs in large vessel occlusion acute ischemic stroke (AIS-LVO) patients vary widely despite achieving successful reperfusion. Prolonged venous transit (PVT+) is a new marker of poor venous outflow on pretreatment perfusion imaging associated with various patient outcomes. We aim to explore the relationship between PVT + and acute care cost estimates for AIS-LVO.

Methods: Adult AIS-LVO patients achieving successful reperfusion with thrombectomy at three centers in the United States were retrospectively reviewed. Cost estimates were derived from national averages for services in the Centers for Medicare and Medicaid Services data (2025). The primary outcome was total cost estimates for acute intervention, imaging, and post-treatment inpatient care until discharge. Estimates were compared between PVT + and PVT- cohorts.

Results: In 109 included patients, the median age was 71 years (IQR 62-80). The cost estimates for total acute stroke care were significantly greater by $11787 in PVT + patients (median $36601 [IQR $24814-$72944] than PVT- patients (median $24814 [IQR $16956-$48388], p = 0.03). Cost of post-treatment care was significantly greater in PVT + patients than PVT- patients (p = 0.03).

Conclusion: PVT + demonstrates potential as a useful, versatile pretreatment biomarker, in conjunction with other clinical data, to anticipate in-hospital resources and costs associated with acute stroke care.

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来源期刊
Neuroradiology
Neuroradiology 医学-核医学
CiteScore
5.30
自引率
3.60%
发文量
214
审稿时长
4-8 weeks
期刊介绍: Neuroradiology aims to provide state-of-the-art medical and scientific information in the fields of Neuroradiology, Neurosciences, Neurology, Psychiatry, Neurosurgery, and related medical specialities. Neuroradiology as the official Journal of the European Society of Neuroradiology receives submissions from all parts of the world and publishes peer-reviewed original research, comprehensive reviews, educational papers, opinion papers, and short reports on exceptional clinical observations and new technical developments in the field of Neuroimaging and Neurointervention. The journal has subsections for Diagnostic and Interventional Neuroradiology, Advanced Neuroimaging, Paediatric Neuroradiology, Head-Neck-ENT Radiology, Spine Neuroradiology, and for submissions from Japan. Neuroradiology aims to provide new knowledge about and insights into the function and pathology of the human nervous system that may help to better diagnose and treat nervous system diseases. Neuroradiology is a member of the Committee on Publication Ethics (COPE) and follows the COPE core practices. Neuroradiology prefers articles that are free of bias, self-critical regarding limitations, transparent and clear in describing study participants, methods, and statistics, and short in presenting results. Before peer-review all submissions are automatically checked by iThenticate to assess for potential overlap in prior publication.
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