{"title":"评估方法假设对美国女性致病人乳头瘤病毒感染的估计年龄的影响","authors":"Alhaji Cherif, Xuedan You, John Cook, Miriam Reuschenbach, Ya-Ting Chen, Craig Roberts, Ruifeng Xu","doi":"10.1093/ofid/ofaf548","DOIUrl":null,"url":null,"abstract":"<p><p>We adapted a previous discrete event simulation model to assess the impact of varying time distributions from disease-causal human papillomavirus (HPV) infection to CIN2+ onset on the estimated age distribution of disease-casual infection in the United States. Differences in these assumptions had minimal effect on estimates, underscoring the importance of expanded HPV vaccination.</p>","PeriodicalId":19517,"journal":{"name":"Open Forum Infectious Diseases","volume":"12 9","pages":"ofaf548"},"PeriodicalIF":3.8000,"publicationDate":"2025-09-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12448938/pdf/","citationCount":"0","resultStr":"{\"title\":\"Assessing the Impact of Methodological Assumptions on Estimated Age of Disease-Causal Human Papillomavirus Infection in US Females.\",\"authors\":\"Alhaji Cherif, Xuedan You, John Cook, Miriam Reuschenbach, Ya-Ting Chen, Craig Roberts, Ruifeng Xu\",\"doi\":\"10.1093/ofid/ofaf548\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>We adapted a previous discrete event simulation model to assess the impact of varying time distributions from disease-causal human papillomavirus (HPV) infection to CIN2+ onset on the estimated age distribution of disease-casual infection in the United States. Differences in these assumptions had minimal effect on estimates, underscoring the importance of expanded HPV vaccination.</p>\",\"PeriodicalId\":19517,\"journal\":{\"name\":\"Open Forum Infectious Diseases\",\"volume\":\"12 9\",\"pages\":\"ofaf548\"},\"PeriodicalIF\":3.8000,\"publicationDate\":\"2025-09-10\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12448938/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Open Forum Infectious Diseases\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.1093/ofid/ofaf548\",\"RegionNum\":4,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2025/9/1 0:00:00\",\"PubModel\":\"eCollection\",\"JCR\":\"Q2\",\"JCRName\":\"IMMUNOLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Open Forum Infectious Diseases","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1093/ofid/ofaf548","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2025/9/1 0:00:00","PubModel":"eCollection","JCR":"Q2","JCRName":"IMMUNOLOGY","Score":null,"Total":0}
Assessing the Impact of Methodological Assumptions on Estimated Age of Disease-Causal Human Papillomavirus Infection in US Females.
We adapted a previous discrete event simulation model to assess the impact of varying time distributions from disease-causal human papillomavirus (HPV) infection to CIN2+ onset on the estimated age distribution of disease-casual infection in the United States. Differences in these assumptions had minimal effect on estimates, underscoring the importance of expanded HPV vaccination.
期刊介绍:
Open Forum Infectious Diseases provides a global forum for the publication of clinical, translational, and basic research findings in a fully open access, online journal environment. The journal reflects the broad diversity of the field of infectious diseases, and focuses on the intersection of biomedical science and clinical practice, with a particular emphasis on knowledge that holds the potential to improve patient care in populations around the world. Fully peer-reviewed, OFID supports the international community of infectious diseases experts by providing a venue for articles that further the understanding of all aspects of infectious diseases.