Stefano Montanari, Ben J Lee, Sam D Blacker, Matthew D Cook, Mark E T Willems
{"title":"新西兰黑加仑提取物对男性低强度持续间歇性收缩期间的生理和心血管反应没有影响。","authors":"Stefano Montanari, Ben J Lee, Sam D Blacker, Matthew D Cook, Mark E T Willems","doi":"10.1007/s00421-025-05971-3","DOIUrl":null,"url":null,"abstract":"<p><strong>Purpose: </strong>Intake of anthocyanin-rich supplements such as New Zealand blackcurrant (NZBC) extract for 7 days showed beneficial effects on cardiovascular function at rest and during moderate and high-intensity exercise. The effects of 4- and 7-day intake of 600 mg of NZBC extract on cardiovascular function, femoral artery diameter, muscle force, muscle activity and muscle fatigue during low-intensity sustained intermittent isometric contractions were examined.</p><p><strong>Methods: </strong>Fifteen healthy males (age: 25 ± 6 years, height: 180 ± 7 cm, body mass: 82 ± 8 kg) visited the laboratory on five occasions (familiarisation, days 4 and 7 of placebo (PLA) or NZBC extract intake). Each visit required the participants to hold the isometric contraction of the m.quadriceps femoris at 10% of their isometric maximal voluntary contraction (iMVC) for 5 bouts of 2-min. At the end of each 2-min, an iMVC was performed with subsequent 20 s rest before starting a subsequent bout. Electromyography, isometric muscle force, hemodynamic and ultrasound data were recorded.</p><p><strong>Results: </strong>At days 4 and 7, there were no effects for NZBC extract on systolic blood pressure, diastolic blood pressure, heart rate, cardiac output, stroke volume, total peripheral resistance and femoral artery diameter. Although the isometric contraction protocol resulted in fatigue, there were no differences between PLA and NZBC extract conditions for isometric muscle force and muscle activity at days 4 and 7 (P > 0.05).</p><p><strong>Conclusion: </strong>NZBC extract had no effect on cardiovascular function and exercise-induced fatigue during repeated bouts of low-intensity sustained intermittent isometric contractions of the m.quadriceps femoris, maybe due to the low demand of the exercise model.</p>","PeriodicalId":12005,"journal":{"name":"European Journal of Applied Physiology","volume":" ","pages":""},"PeriodicalIF":2.7000,"publicationDate":"2025-09-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"New Zealand blackcurrant extract has no effect on physiological and cardiovascular responses during low-intensity sustained intermittent isometric contractions in men.\",\"authors\":\"Stefano Montanari, Ben J Lee, Sam D Blacker, Matthew D Cook, Mark E T Willems\",\"doi\":\"10.1007/s00421-025-05971-3\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Purpose: </strong>Intake of anthocyanin-rich supplements such as New Zealand blackcurrant (NZBC) extract for 7 days showed beneficial effects on cardiovascular function at rest and during moderate and high-intensity exercise. The effects of 4- and 7-day intake of 600 mg of NZBC extract on cardiovascular function, femoral artery diameter, muscle force, muscle activity and muscle fatigue during low-intensity sustained intermittent isometric contractions were examined.</p><p><strong>Methods: </strong>Fifteen healthy males (age: 25 ± 6 years, height: 180 ± 7 cm, body mass: 82 ± 8 kg) visited the laboratory on five occasions (familiarisation, days 4 and 7 of placebo (PLA) or NZBC extract intake). Each visit required the participants to hold the isometric contraction of the m.quadriceps femoris at 10% of their isometric maximal voluntary contraction (iMVC) for 5 bouts of 2-min. At the end of each 2-min, an iMVC was performed with subsequent 20 s rest before starting a subsequent bout. Electromyography, isometric muscle force, hemodynamic and ultrasound data were recorded.</p><p><strong>Results: </strong>At days 4 and 7, there were no effects for NZBC extract on systolic blood pressure, diastolic blood pressure, heart rate, cardiac output, stroke volume, total peripheral resistance and femoral artery diameter. Although the isometric contraction protocol resulted in fatigue, there were no differences between PLA and NZBC extract conditions for isometric muscle force and muscle activity at days 4 and 7 (P > 0.05).</p><p><strong>Conclusion: </strong>NZBC extract had no effect on cardiovascular function and exercise-induced fatigue during repeated bouts of low-intensity sustained intermittent isometric contractions of the m.quadriceps femoris, maybe due to the low demand of the exercise model.</p>\",\"PeriodicalId\":12005,\"journal\":{\"name\":\"European Journal of Applied Physiology\",\"volume\":\" \",\"pages\":\"\"},\"PeriodicalIF\":2.7000,\"publicationDate\":\"2025-09-22\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"European Journal of Applied Physiology\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.1007/s00421-025-05971-3\",\"RegionNum\":3,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q2\",\"JCRName\":\"PHYSIOLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"European Journal of Applied Physiology","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1007/s00421-025-05971-3","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"PHYSIOLOGY","Score":null,"Total":0}
New Zealand blackcurrant extract has no effect on physiological and cardiovascular responses during low-intensity sustained intermittent isometric contractions in men.
Purpose: Intake of anthocyanin-rich supplements such as New Zealand blackcurrant (NZBC) extract for 7 days showed beneficial effects on cardiovascular function at rest and during moderate and high-intensity exercise. The effects of 4- and 7-day intake of 600 mg of NZBC extract on cardiovascular function, femoral artery diameter, muscle force, muscle activity and muscle fatigue during low-intensity sustained intermittent isometric contractions were examined.
Methods: Fifteen healthy males (age: 25 ± 6 years, height: 180 ± 7 cm, body mass: 82 ± 8 kg) visited the laboratory on five occasions (familiarisation, days 4 and 7 of placebo (PLA) or NZBC extract intake). Each visit required the participants to hold the isometric contraction of the m.quadriceps femoris at 10% of their isometric maximal voluntary contraction (iMVC) for 5 bouts of 2-min. At the end of each 2-min, an iMVC was performed with subsequent 20 s rest before starting a subsequent bout. Electromyography, isometric muscle force, hemodynamic and ultrasound data were recorded.
Results: At days 4 and 7, there were no effects for NZBC extract on systolic blood pressure, diastolic blood pressure, heart rate, cardiac output, stroke volume, total peripheral resistance and femoral artery diameter. Although the isometric contraction protocol resulted in fatigue, there were no differences between PLA and NZBC extract conditions for isometric muscle force and muscle activity at days 4 and 7 (P > 0.05).
Conclusion: NZBC extract had no effect on cardiovascular function and exercise-induced fatigue during repeated bouts of low-intensity sustained intermittent isometric contractions of the m.quadriceps femoris, maybe due to the low demand of the exercise model.
期刊介绍:
The European Journal of Applied Physiology (EJAP) aims to promote mechanistic advances in human integrative and translational physiology. Physiology is viewed broadly, having overlapping context with related disciplines such as biomechanics, biochemistry, endocrinology, ergonomics, immunology, motor control, and nutrition. EJAP welcomes studies dealing with physical exercise, training and performance. Studies addressing physiological mechanisms are preferred over descriptive studies. Papers dealing with animal models or pathophysiological conditions are not excluded from consideration, but must be clearly relevant to human physiology.