{"title":"探讨无创迷走神经刺激治疗耐药癫痫的疗效。","authors":"Daleena Prathiba Madda, Sruthi Vempatapu, Sasikanth Kanaganuru","doi":"10.6026/973206300211551","DOIUrl":null,"url":null,"abstract":"<p><p>Drug-resistant epilepsy (DRE) affects approximately 30% of individuals with epilepsy who do not respond to antiepileptic drugs. This randomized controlled trial evaluated the efficacy of non-invasive vagus nerve stimulation (nVNS) in 120 DRE patients. Over 12 weeks, the intervention group showed a 45% reduction in seizures and a 30% improvement in quality of life, both statistically significant. Minor side effects included headaches and neck discomfort. nVNS appears to be a safe and effective adjunctive therapy for managing DRE.</p>","PeriodicalId":8962,"journal":{"name":"Bioinformation","volume":"21 6","pages":"1551-1554"},"PeriodicalIF":1.9000,"publicationDate":"2025-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12449518/pdf/","citationCount":"0","resultStr":"{\"title\":\"Investigating the efficacy of non-invasive vagus nerve stimulation in treating drug-resistant epilepsy.\",\"authors\":\"Daleena Prathiba Madda, Sruthi Vempatapu, Sasikanth Kanaganuru\",\"doi\":\"10.6026/973206300211551\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>Drug-resistant epilepsy (DRE) affects approximately 30% of individuals with epilepsy who do not respond to antiepileptic drugs. This randomized controlled trial evaluated the efficacy of non-invasive vagus nerve stimulation (nVNS) in 120 DRE patients. Over 12 weeks, the intervention group showed a 45% reduction in seizures and a 30% improvement in quality of life, both statistically significant. Minor side effects included headaches and neck discomfort. nVNS appears to be a safe and effective adjunctive therapy for managing DRE.</p>\",\"PeriodicalId\":8962,\"journal\":{\"name\":\"Bioinformation\",\"volume\":\"21 6\",\"pages\":\"1551-1554\"},\"PeriodicalIF\":1.9000,\"publicationDate\":\"2025-06-30\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12449518/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Bioinformation\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.6026/973206300211551\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2025/1/1 0:00:00\",\"PubModel\":\"eCollection\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Bioinformation","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.6026/973206300211551","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2025/1/1 0:00:00","PubModel":"eCollection","JCR":"","JCRName":"","Score":null,"Total":0}
Investigating the efficacy of non-invasive vagus nerve stimulation in treating drug-resistant epilepsy.
Drug-resistant epilepsy (DRE) affects approximately 30% of individuals with epilepsy who do not respond to antiepileptic drugs. This randomized controlled trial evaluated the efficacy of non-invasive vagus nerve stimulation (nVNS) in 120 DRE patients. Over 12 weeks, the intervention group showed a 45% reduction in seizures and a 30% improvement in quality of life, both statistically significant. Minor side effects included headaches and neck discomfort. nVNS appears to be a safe and effective adjunctive therapy for managing DRE.
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