保乳手术切缘对局部复发率的影响。

IF 1.9
Bioinformation Pub Date : 2025-06-30 eCollection Date: 2025-01-01 DOI:10.6026/973206300211631
Rakshana Munusamy, Mohammed Mohsen Abdel Raouf, Shakthiyan Gopal, J Naveen Bose, Manisha Mohammed Shaan, Kaushik J
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引用次数: 0

摘要

在乳腺癌的早期阶段,保守的乳房手术干预作为一种适当的治疗选择被广泛接受,并被推荐用于建立肿瘤安全性,同时实现乳房的美观。因此,对150名接受保乳手术的患者进行为期5年的随访,了解手术切缘状态(可能报告为阳性、接近或阴性)是有意义的;总体局部复发的平均发生率估计为8%。然而,在切缘阳性的患者中记录到更高的数值为25%。接近和负利润率分别为10%和5%。肿瘤的大小、分级及切缘是判断p复发的重要指标
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Impact of surgical margins on local recurrence rates in breast-conserving surgery.

A conservative surgical breast intervention is broadly acceptable as an appropriate treatment option in preliminary stages of breast cancer and is recommended in order to establish oncologic safety while achieving aesthetics of the breast. Therefore, it is of interest to follow-up for five years among 150 patients who received breast-conserving surgery with an understanding of surgical margin status which might be reported positive, close, or negative; the mean incidence of overall local recurrence is estimated at 8%. Higher values, however, were recorded in positive margin patients of 25%. Close and negative margins were significantly at 10% and 5%, respectively. Tumour size and grade, with the margin, are significant indicators of recurrence of p <0.05. In such findings lies the critical relevance of achieving the surgical margins clean in order to minimize the percentage of local recurrences and have better long term results in a patient with carcinoma breast.

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来源期刊
Bioinformation
Bioinformation MATHEMATICAL & COMPUTATIONAL BIOLOGY-
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